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Pathology

মোট প্রশ্ন৬৭০এই পাতা১০০প্রতি পাতা১০০
ঘনত্ব
উত্তর
উত্তরিতবর্তমানপুনরায় দেখুনঅসম্পূর্ণ

Pathology

PrepBank · পাতা / · ৫০১৬০০ / ৬৭০

৫০১.
Which is the infective form of E. histolytica?
  1. ক) Trophozoites
  2. খ) Mature Quadrinucleate cyst
  3. গ) Cyst
  4. ঘ) Merozoites
সঠিক উত্তর:
খ) Mature Quadrinucleate cyst
উত্তর
সঠিক উত্তর:
খ) Mature Quadrinucleate cyst
ব্যাখ্যা
Mature Quadrinucleate cyst is infective form of E. histolytica
৫০২.
Inflammatory arthritis -
  1. Morning stiffness absent
  2. Joint pain worse after movement
  3. Joint effusion present
  4. Joint crepitation present
সঠিক উত্তর:
Joint effusion present
উত্তর
সঠিক উত্তর:
Joint effusion present
ব্যাখ্যা
Explanation :
Inflammatory arthritis -
Morning stiffness  - present 
Joint pain - Worse after rest and improved after movement 
Temperature - Raised
Joint effusion - Present
Joint crepitation  - Absent
৫০৩.
Which is key determinant of antigen presentation to T-cell?
  1. ক) HLA complex
  2. খ) PTPN22
  3. গ) CTLA4
  4. ঘ) IL23R
সঠিক উত্তর:
ক) HLA complex
উত্তর
সঠিক উত্তর:
ক) HLA complex
ব্যাখ্যা
HLA complex is key determinant of antigen presentation to T-cell.
৫০৪.
Amastigote form of leishmania donovani are detected in:
  1. ক) Infected sandfly
  2. খ) polymorphonuclear leucocytes
  3. গ) bone marrow aspirates
  4. ঘ) Sputum
সঠিক উত্তর:
গ) bone marrow aspirates
উত্তর
সঠিক উত্তর:
গ) bone marrow aspirates
ব্যাখ্যা
Amastigote form of leishmania donovani are detected in bone marrow aspirate
৫০৫.
Diseases caused by viridans streptococcus
  1. ক) Erysipelas
  2. খ) Endocarditis
  3. গ) Scalded skin syndrome
  4. ঘ) Toxic shock syndrome
সঠিক উত্তর:
খ) Endocarditis
উত্তর
সঠিক উত্তর:
খ) Endocarditis
ব্যাখ্যা
Diseases caused by viridans streptococcus - Endocarditis
৫০৬.
Right-to-left shunts are most commonly caused by
  1. ক) TOF
  2. খ) ASD
  3. গ) VSD
  4. ঘ) PDA
সঠিক উত্তর:
ক) TOF
উত্তর
সঠিক উত্তর:
ক) TOF
ব্যাখ্যা
• Left-to-right shunts are most common and are typically associated with ASDs, VSDs, or a PDA.
৫০৭.
Radiographic hallmarks in RA excludes
  1. ক) Joint effusions
  2. খ) Juxta-articular osteopenia with erosions
  3. গ) Widening of the joint space
  4. ঘ) Loss of articular cartilage
সঠিক উত্তর:
গ) Widening of the joint space
উত্তর
সঠিক উত্তর:
গ) Widening of the joint space
ব্যাখ্যা

Radiographic hallmarks are
• Joint effusions
• Juxta-articular osteopenia with erosions
• Narrowing of the joint space
• Loss of articular cartilage

৫০৮.
Which resembles necrosis morphologically & apoptosis mechanistically?
  1. ক) Pyroptosis
  2. খ) Necroptosis
  3. গ) Aponecrosis
  4. ঘ) Necropyroptosis
সঠিক উত্তর:
খ) Necroptosis
উত্তর
সঠিক উত্তর:
খ) Necroptosis
৫০৯.
Memory cells are present in case of -
  1. ক) Eosinophil
  2. খ) B lymphocyte
  3. গ) Mast cell
  4. ঘ) Macrophage
সঠিক উত্তর:
খ) B lymphocyte
উত্তর
সঠিক উত্তর:
খ) B lymphocyte
ব্যাখ্যা
Reference: Lange microbiology/14th/P-514
৫১০.
Which is sex cord tumor of ovary according to WHO -
  1. Seminoma
  2. Teratoma
  3. Granulosa cell tumor
  4. Choriocarcinoma
সঠিক উত্তর:
Granulosa cell tumor
উত্তর
সঠিক উত্তর:
Granulosa cell tumor
ব্যাখ্যা
Explanation :
Sex cord tumor of ovary -
Leydig cell tumor
Sertoli cell tumor
Granulosa cell tumor
Thecoma
Fibroma
৫১১.
Complement products are produced in
  1. ক) Liver
  2. খ) Kidney
  3. গ) Oral mucosa
  4. ঘ) Gall bladder
সঠিক উত্তর:
ক) Liver
উত্তর
সঠিক উত্তর:
ক) Liver
ব্যাখ্যা
Complement products are produced in liver
৫১২.
Oedema in acute inflammation occurs due to -
  1. Endothelial contraction
  2. Increased viscosity of blood
  3. Action of macrophage in cell
  4. Attempts of tissue healing
সঠিক উত্তর:
Endothelial contraction
উত্তর
সঠিক উত্তর:
Endothelial contraction
ব্যাখ্যা
Explanation 
Acute inflammatory oedema is due to -
Increased vascular permeability by endothelial cell contraction
Increased capillary hydrostatic pressure 
Breakdown of large molecules of tissue proteins
Increased fluidity of the tissue ground substance. 
৫১৩.
Connective tissue metaplasia occurs in
  1. ক) Myositis ossificans
  2. খ) Bile duct obstruction
  3. গ) Habitual smoker
  4. ঘ) Barrett oesophagus
সঠিক উত্তর:
ক) Myositis ossificans
উত্তর
সঠিক উত্তর:
ক) Myositis ossificans
ব্যাখ্যা
Connective tissue metaplasia occurs in myositis ossificans
৫১৪.
Chronic rheumatic heart disease is usually affecting which of the following heart valve?
  1. ক) Aortic
  2. খ) Pulmonary
  3. গ) Mitral
  4. ঘ) Tricuspid
সঠিক উত্তর:
গ) Mitral
উত্তর
সঠিক উত্তর:
গ) Mitral
ব্যাখ্যা
Explanation: Chronic rheumatic heart disease most commonly affects the mitral valve and is responsible for 99% of acquired mitral stenosis
৫১৫.
Most important risk factor for chronic bronchitis
  1. ক) Smoking
  2. খ) Genetic predisposition
  3. গ) Air pollutant
  4. ঘ) Atopy
সঠিক উত্তর:
ক) Smoking
উত্তর
সঠিক উত্তর:
ক) Smoking
ব্যাখ্যা
Cigarette smoking is the most important risk factor; air pollutants also contribute.
৫১৬.
Signs of hyperthyroidism -
  1. Bradycardia
  2. Peripheral oedema
  3. Puffy face
  4. Tremor
সঠিক উত্তর:
Tremor
উত্তর
সঠিক উত্তর:
Tremor
ব্যাখ্যা
Explanation -
Signs of hyperthyroidism -
Exopthalmos
Lid retraction or lag
Tachycardia
Atrial fibrillation 
Tremor
HTN
Goiter
Warm,moist skin
Muscle weakness
Pretibial myxoedema
৫১৭.
Causes of conjugated hyperbulirubinemia -
  1. Hemolytic anaemia
  2. Gilbert syndrome
  3. Physiologic jaundice
  4. Autoimmune cholangiopathies
সঠিক উত্তর:
Autoimmune cholangiopathies
উত্তর
সঠিক উত্তর:
Autoimmune cholangiopathies
ব্যাখ্যা
Explanation :
Unconjugated hyperbilirubinemia -
Haemolytic anaemia
Ineffective erythropoiesis
Reduced hepatic uptake
Breast milk jaundice
Physiologic jaundice
Gilbert syndrome
Conjugated hyperbilirubinemia -
Dublin johnson syndrome
Autoimmune cholangiopathies
৫১৮.
Cardinal signs of inflammation ‘calor’ means: -
  1. ক) Redness
  2. খ) Swelling
  3. গ) Heat
  4. ঘ) Pain
সঠিক উত্তর:
গ) Heat
উত্তর
সঠিক উত্তর:
গ) Heat
ব্যাখ্যা
[Robbins 9th 71]
৫১৯.
Major criteria of rheumatic fever -
  1. Fever
  2. Arthalgia
  3. Chorea
  4. Raised ESR
সঠিক উত্তর:
Chorea
উত্তর
সঠিক উত্তর:
Chorea
ব্যাখ্যা
Explanation :
Major criteria of rheumatic fever :
Carditis 
Polyarthritis( migratory) 
Chorea
Erythema marginatum
Subcutaneous nodules
Minor criteria :
Fever
Arthalgia
Previous rheumatic fever
Raised ESR
Leucocytosis
First degree AV block
৫২০.
Which of the following is the most common congenital heart disease?
  1. ক) ASD
  2. খ) VSD
  3. গ) PDA
  4. ঘ) TOF
সঠিক উত্তর:
খ) VSD
উত্তর
সঠিক উত্তর:
খ) VSD
ব্যাখ্যা
Explanation: VSD is the most common congenital heart disease
৫২১.
Regarding giardiasis, which one is correct?
  1. ক) Fever
  2. খ) Invasive
  3. গ) Bloody diarrhoea
  4. ঘ) Malabsorption
সঠিক উত্তর:
ঘ) Malabsorption
উত্তর
সঠিক উত্তর:
ঘ) Malabsorption
ব্যাখ্যা
Explanation: After incubation period, there is diarrhoea, abdominal pain, weakness, anorexia, nausea and vomiting. On examination, there may be abdominal distension and tenderness, Chronic diarrhea and malabsorption may occur, with bulky
৫২২.
Which is not the target organ damage by hypertension -
  1. Blood vessels
  2. CNS
  3. Liver
  4. Kidneys
সঠিক উত্তর:
Liver
উত্তর
সঠিক উত্তর:
Liver
ব্যাখ্যা
Explanation :
Target organ damage by hypertension -
Blood vessels
Central nervous system 
Retina
Heart
Kidneys
৫২৩.
Cells implicated in tumor immunity -
  1. Natural killer cell
  2. Neutrophil
  3. Eosinophil
  4. Plasma cell
সঠিক উত্তর:
Natural killer cell
উত্তর
সঠিক উত্তর:
Natural killer cell
ব্যাখ্যা
Explanation :
Cells implicated tumor immunity -
Natural killer cell
Macrophage
Cytotoxic T cell
৫২৪.
Hyperacute liver failure time limit -
  1. 7 days
  2. 28 days
  3. 3 months
  4. 1 year
সঠিক উত্তর:
7 days
উত্তর
সঠিক উত্তর:
7 days
ব্যাখ্যা
Explanation :
Liver failure -
Hyperacute : <7  days
Acute : 8-28 days
Subacute : 29 days - 12 weeks.
৫২৫.
Liver Flukes includes following:
  1. ক) Schistosoma
  2. খ) Clonorchis sinensis
  3. গ) Giardia
  4. ঘ) D. Latum
সঠিক উত্তর:
খ) Clonorchis sinensis
উত্তর
সঠিক উত্তর:
খ) Clonorchis sinensis
ব্যাখ্যা
sinensis is liver fluke
৫২৬.
Molecules involved in septic shock
  1. ক) Neutrophils
  2. খ) Eosinophils
  3. গ) Cytokines
  4. ঘ) Monocytes
সঠিক উত্তর:
গ) Cytokines
উত্তর
সঠিক উত্তর:
গ) Cytokines
৫২৭.
Major neurodegenerative disorder -
  1. Acute polyneuropathy
  2. Alzheimer’s disease
  3. Encephalomyelitis
  4. Poliomyelitis
সঠিক উত্তর:
Alzheimer’s disease
উত্তর
সঠিক উত্তর:
Alzheimer’s disease
ব্যাখ্যা
Explanation :
Major neurodegenerative disorder :
Alzheimer’s disese
Parkinson disese
Huntington disese
Spinocerebellar ataxia
৫২৮.
Insulin dependent diabetes malitus ( IDDM) -
  1. Age <40 years
  2. Obase
  3. No ketonuria
  4. Family history of DM
সঠিক উত্তর:
Age <40 years
উত্তর
সঠিক উত্তর:
Age <40 years
ব্যাখ্যা
Explanation -
IDDM -
Age <40 years
Duration : Weeks
Body weight : Normal or low
Ketonuria, Hypoglycemia, complications : Present
Family history : Absent
Othet autoimmune disease : Present
৫২৯.
Which of the following is the hallmark of SLE?
  1. ক) Oral ulcer
  2. খ) Joint hypermobility
  3. গ) Skin rash
  4. ঘ) Production of autoantibodies
সঠিক উত্তর:
ঘ) Production of autoantibodies
উত্তর
সঠিক উত্তর:
ঘ) Production of autoantibodies
ব্যাখ্যা
Explanation: The hallmark of SLE is the production of autoantibodies Antibodies to double-stranded DNA and the so-called Smith (Sm) antigen are virtually diagnostic of SLE.
৫৩০.
ACTH is related to following paraneuplastic syndrome -
  1. Hypercalcemia
  2. Cushing syndrome
  3. Syndrome of inappropriate ADH
  4. Hypoglycemia
সঠিক উত্তর:
Cushing syndrome
উত্তর
সঠিক উত্তর:
Cushing syndrome
৫৩১.
Urine routine microscopic examination detect following except -
  1. Osmolality
  2. pH
  3. Protein
  4. Urinary bicarbonate
সঠিক উত্তর:
Urinary bicarbonate
উত্তর
সঠিক উত্তর:
Urinary bicarbonate
ব্যাখ্যা
Explanation -
Urine R/M (Urine Routine & Microscopy) test involves gross, chemical, and microscopic evaluation of the urine sample.
Include physical appearence, urine protein, sugar, ketone body level,osmolarity,pH.
৫৩২.
Which antibody associated with SLE except -
  1. Anti Ds DNA
  2. ANA
  3. Anti Sm antibody
  4. ACPA
সঠিক উত্তর:
ACPA
উত্তর
সঠিক উত্তর:
ACPA
ব্যাখ্যা
Explanation -
Antibody raised in SLE :
ANA
Anti Ds DNA
Anti phospholipid antibody
Anti Sm antibody 

ACPA is anti citrullinated peptide antibodies raised in rheumatoid arthritis. 
৫৩৩.
Metastatic gastrointestinal tumor-
  1. ক) Cystadenocarcinoma
  2. খ) Kulchitsky cell tumour
  3. গ) Adenocarcinoma
  4. ঘ) Krukenberge tumour
সঠিক উত্তর:
ঘ) Krukenberge tumour
উত্তর
সঠিক উত্তর:
ঘ) Krukenberge tumour
ব্যাখ্যা
Krukenbegre tumor is metastatise to ovary from stomach
৫৩৪.
Which is not childhood benign carcinoma -
  1. Haemangioma
  2. Neuroblastoma
  3. Benign fibrous tumor
  4. Mature teratoma
সঠিক উত্তর:
Neuroblastoma
উত্তর
সঠিক উত্তর:
Neuroblastoma
ব্যাখ্যা
Explanation -
Benign childhood tumor -
Haemangioma
Lymphangioma
Benign fibrous tumor
Mature teratoma
৫৩৫.
Most characteristic feature of apoptosis is
  1. ক) Chromatin condensation
  2. খ) Cell shrinkage
  3. গ) Formation of apoptotic bodies
  4. ঘ) Formation of bleb
সঠিক উত্তর:
ক) Chromatin condensation
উত্তর
সঠিক উত্তর:
ক) Chromatin condensation
ব্যাখ্যা
Most characteristic feature of apoptosis is chromatin condensation
৫৩৬.
Shrinkage in size of cell by loss of cell substance is called
  1. ক) Atrophy
  2. খ) Hypertrophy
  3. গ) Metaplasia
  4. ঘ) Anaplasia
সঠিক উত্তর:
ক) Atrophy
উত্তর
সঠিক উত্তর:
ক) Atrophy
ব্যাখ্যা
Shrinkage in size of cell by loss of cell substance is called atrophy
৫৩৭.
Cytokine of acute inflammation -
  1. IL-1
  2. IL-12
  3. Gumma interferon
  4. IL-17
সঠিক উত্তর:
IL-1
উত্তর
সঠিক উত্তর:
IL-1
ব্যাখ্যা
Explanation :
Cytokine of acute inflammation :
TNF, IL-1, IL-6, Chemokines
Cytokine of chronic inflammation :
IL-12, Gumma interferon, IL-17, All mediators of acute inflammation 
৫৩৮.
Most common complications of pneumonia -
  1. Bronchial asthma
  2. Para -pneumonic effusion
  3. Hepatitis
  4. Pulmonary embolism
সঠিক উত্তর:
Para -pneumonic effusion
উত্তর
সঠিক উত্তর:
Para -pneumonic effusion
ব্যাখ্যা
Explanation :
Complications of pneumonia-
Para- pneumonic effusion ( most common)
Empyema
Lung abscess
Lober collapse
Hepatitis,pericarditis
DVT
ARDS
Pneumothorax
৫৩৯.
Ascariasis is caused by which of the following parasite?
  1. ক) Necator americanus
  2. খ) Ancylostoma duodenale
  3. গ) Ascaris lumbricoides
  4. ঘ) Strongyloides stercoralis
সঠিক উত্তর:
গ) Ascaris lumbricoides
উত্তর
সঠিক উত্তর:
গ) Ascaris lumbricoides
ব্যাখ্যা
Explanation: Ascaris lumbricoides causes ascariasis.
৫৪০.
White infarct occurs in
  1. ক) Intestine
  2. খ) Spleen
  3. গ) Lung
  4. ঘ) Ovary
সঠিক উত্তর:
খ) Spleen
উত্তর
সঠিক উত্তর:
খ) Spleen
ব্যাখ্যা
White infarct occurs in spleen
৫৪১.
Which is not the symptoms of Rheumatic carditis -
  1. Dyspnea
  2. Chest pain
  3. Pulmonary oedema
  4. Swelling of the legs
সঠিক উত্তর:
Pulmonary oedema
উত্তর
সঠিক উত্তর:
Pulmonary oedema
ব্যাখ্যা
Explanation -
Symptoms of rheumatic carditis -
Dyspnoea 
Syncope
Chest pain,palpitation
Swelling of the legs.
৫৪২.
Pathogenesis of osteoporosis -
  1. Increased bone dexa scan
  2. Increased osteocyte formation
  3. Hyperparathyroidism
  4. Drug - DMRD
সঠিক উত্তর:
Hyperparathyroidism
উত্তর
সঠিক উত্তর:
Hyperparathyroidism
ব্যাখ্যা
Explanation :
Pathogenesis of osteoporosis -
Postmenopausal due to low peak bone mass
Genetic cause
Hypogonadism
Inflammatory bowel disease
Hyperparathyroidism
Cushing syndrome 
Corticosteroid 
GnRH agonist therapy
Alcohol excess
Heparin therapy
৫৪৩.
Which of the following is the most common GIT carcinoma?
  1. ক) Ca oesophagus
  2. খ) Ca rectum
  3. গ) Ca colon
  4. ঘ) Ca stomach
সঠিক উত্তর:
গ) Ca colon
উত্তর
সঠিক উত্তর:
গ) Ca colon
ব্যাখ্যা
Explanation: Adenocarcinoma of the colon is the most common malignancy of the GI tract and is a major cause of morbidity and mortality worldwide
৫৪৪.
AGN -
  1. History of previous pharyngitis
  2. Age :2-6 years
  3. Haematuria - Absent
  4. Massive proteinuria
সঠিক উত্তর:
History of previous pharyngitis
উত্তর
সঠিক উত্তর:
History of previous pharyngitis
ব্যাখ্যা
Explanation :
AGN -
Age group : 6-12 years
Haematuria : Present
Hypertension : Present
Mild to moderate proteiniurea
৫৪৫.
Oral route is the main portal of entry for following virus -
  1. Japanes B encephalitis virus
  2. Rubella virus
  3. Hepatitis A virus
  4. Hepatitis C virus
সঠিক উত্তর:
Hepatitis A virus
উত্তর
সঠিক উত্তর:
Hepatitis A virus
ব্যাখ্যা
Explanation -
Transmission through Feco-oral route :
Hepatiris A & E
Polio
Rota
Coxsackie
Echo
Nowwalk virus
৫৪৬.
Regarding H.pylori, which one is correct?
  1. ক) Gram positive
  2. খ) Non motile
  3. গ) Comma shaped
  4. ঘ) Multiple flagella
সঠিক উত্তর:
ঘ) Multiple flagella
উত্তর
সঠিক উত্তর:
ঘ) Multiple flagella
ব্যাখ্যা
Explanation: H. pylori is Gram-negative and spiral, and has multiple flagella at one end, which make it motile, allowing it to burrow and live beneath the mucus layer adherent to the epithelial surface.
৫৪৭.
Which of the following is the most common risk factor for developing hepatocellular carcinoma?
  1. ক) HBV infection
  2. খ) HCV infection
  3. গ) Alcohol
  4. ঘ) NASH
সঠিক উত্তর:
ক) HBV infection
উত্তর
সঠিক উত্তর:
ক) HBV infection
ব্যাখ্যা
Explanation: HBV infection is the most common risk factor for developing hepatocellular carcinoma.
৫৪৮.
Most frequent presentation of RPGN
  1. ক) Posts infectious Glomerulodisease
  2. খ) Goodpasture syndrome
  3. গ) Minimal change disease
  4. ঘ) IgA nephritis
সঠিক উত্তর:
খ) Goodpasture syndrome
উত্তর
সঠিক উত্তর:
খ) Goodpasture syndrome
৫৪৯.
Granulation tissue easily bleeds on touch due to rupture of
  1. ক) New capillaries
  2. খ) New venules
  3. গ) New arterioles
  4. ঘ) New arteries
সঠিক উত্তর:
ক) New capillaries
উত্তর
সঠিক উত্তর:
ক) New capillaries
ব্যাখ্যা
Granulation tissue easily bleeds on touch due to rupture of new capillaries
৫৫০.
Emigration of leukocyte to the site of injury is called-
  1. ক) Phagocytosis
  2. খ) Chemotaxis
  3. গ) Diapedesis
  4. ঘ) Rolling
সঠিক উত্তর:
খ) Chemotaxis
উত্তর
সঠিক উত্তর:
খ) Chemotaxis
ব্যাখ্যা
Emigration of leukocyte to the site of injury is called chemotaxis
৫৫১.
The vector and definitive host for plasmodia is the
  1. ক) Human
  2. খ) Housefly
  3. গ) Sandfly
  4. ঘ) Female Anopheles mosquito
সঠিক উত্তর:
ঘ) Female Anopheles mosquito
উত্তর
সঠিক উত্তর:
ঘ) Female Anopheles mosquito
ব্যাখ্যা
The vector and definitive host for plasmodia is the female Anopheles mosquito
৫৫২.
Which one is double edged sword?
  1. ক) Atrophy
  2. খ) Hypertrophy
  3. গ) Hyperplasia
  4. ঘ) Metaplasia
সঠিক উত্তর:
ঘ) Metaplasia
উত্তর
সঠিক উত্তর:
ঘ) Metaplasia
ব্যাখ্যা

• Metaplasia is a reversible change in which one differentiated cell type (epithelial or mesenchymal) is replaced by another cell type.
• Epithelial metaplasia is a double-edged sword
• It’s of 2 types. Epithelial & connective tissue metaplasia
• The most common epithelial metaplasia is columnar to squamous as occurs in the respiratory tract in response to chronic irritation.

৫৫৩.
Shape of pneumococcus
  1. ক) Ring
  2. খ) Lancet
  3. গ) Bullet
  4. ঘ) Wedge
সঠিক উত্তর:
খ) Lancet
উত্তর
সঠিক উত্তর:
খ) Lancet
ব্যাখ্যা
• The presence of numerous neutrophils containing the typical gram-positive, lancet-shaped diplococci supports the diagnosis of pneumococcal pneumonia
৫৫৪.
Which hepatocellular adenoma has very high risk of malignant transformation
  1. ক) HNF1-alpha inactivated adenoma
  2. খ) Beta catenin activated adenoma
  3. গ) Inflammatory adenoma
  4. ঘ) None of them
সঠিক উত্তর:
খ) Beta catenin activated adenoma
উত্তর
সঠিক উত্তর:
খ) Beta catenin activated adenoma
৫৫৫.
Seropositive arthritis -
  1. Septic arthritis
  2. Rheumatoid arthritis
  3. IBD associated arthopathy
  4. Gout
সঠিক উত্তর:
Rheumatoid arthritis
উত্তর
সঠিক উত্তর:
Rheumatoid arthritis
ব্যাখ্যা
Explanation :
Seropositive arthritis -
Rheumatoid arthritis 
Systemic lupus erythromatosus ( SLE) 
৫৫৬.
Antigen test usually used for diagnosis of
  1. ক) HAV
  2. খ) HBV
  3. গ) HCV
  4. ঘ) HDV
সঠিক উত্তর:
খ) HBV
উত্তর
সঠিক উত্তর:
খ) HBV
৫৫৭.
Disuse atrophy is seen in -
  1. Skeletal muscle
  2. Gut
  3. Brain
  4. Uterus
সঠিক উত্তর:
Skeletal muscle
উত্তর
সঠিক উত্তর:
Skeletal muscle
ব্যাখ্যা
Explanation :
Decreased workload or disuse atrophy is seen in skeletal muscle in a patient with restricted to bed rest,or when immobilised in plaster cast.
৫৫৮.
Which is not the cause of sudden cardiac death -
  1. Mitral valve prolapse
  2. Pulmonary hypertension
  3. Myocarditis
  4. Corrected MS
সঠিক উত্তর:
Corrected MS
উত্তর
সঠিক উত্তর:
Corrected MS
ব্যাখ্যা
Explanation :
Causes of sudden cardiac death -
Heriditary or acquired abnormalities of the cardiac conduction system
Congenital coronary artery abnormalities
Mitral valve prolapse
Myocarditis or sarcoidosis
Dilated cardiomyopathy
Pulmonary hypertension
Myocardial hypertrophy 
৫৫৯.
Which of the following is the most common cause of cancer related mortality worldwide?
  1. ক) Breast cancer
  2. খ) Lung Cancer
  3. গ) Leukaemia
  4. ঘ) Gastric cancer
সঠিক উত্তর:
খ) Lung Cancer
উত্তর
সঠিক উত্তর:
খ) Lung Cancer
ব্যাখ্যা
Explanation: Lung cancer is currently the most frequently diagnosed major cancer in the world and the most common cause of cancer mortality worldwide
৫৬০.
Most important risk factor for esophageal adenocarcinoma-
  1. ক) Achalasia cardia
  2. খ) Mallory Weiss tear
  3. গ) Barrett's oesophegus
  4. ঘ) Oesophegeal fistula
সঠিক উত্তর:
গ) Barrett's oesophegus
উত্তর
সঠিক উত্তর:
গ) Barrett's oesophegus
ব্যাখ্যা
Barrett’s oesophagus is most important risk factor for oesophageal adenocarcinoma
৫৬১.
Chronic bronchitis is defined as persistent productive cough for at least …consecutive months in at least 2 consecutive years?
  1. ক) 1
  2. খ) 2
  3. গ) 3
  4. ঘ) 4
সঠিক উত্তর:
গ) 3
উত্তর
সঠিক উত্তর:
গ) 3
ব্যাখ্যা
Chronic bronchitis is defined as persistent productive cough for at least 3 consecutive months in at least 2 consecutive years.
৫৬২.
What is the x-ray finding of Ancylostomiasis?
  1. ক) Collapse
  2. খ) Consolidation
  3. গ) Cavitation
  4. ঘ) Hilar lymphadenopathy
সঠিক উত্তর:
খ) Consolidation
উত্তর
সঠিক উত্তর:
খ) Consolidation
ব্যাখ্যা
Explanation: The passage of the larvae through the lungs in a heavy infection causes a paroxysmal cough with blood-stained sputum, associated with patchy pulmonary consolidation
৫৬৩.
Cause of secondary osteoporosis -
  1. Idiopathic
  2. Postmenopausal
  3. Addisons disease
  4. Senile
সঠিক উত্তর:
Addisons disease
উত্তর
সঠিক উত্তর:
Addisons disease
৫৬৪.
Leptospirainterrogans persist indefinitely in
  1. ক) Mucous membrane
  2. খ) Bowman’s capsule
  3. গ) Juxtaglomerular apparatus
  4. ঘ) Convoluted tubules of the kidney
সঠিক উত্তর:
ঘ) Convoluted tubules of the kidney
উত্তর
সঠিক উত্তর:
ঘ) Convoluted tubules of the kidney
ব্যাখ্যা
Explanation: Leptospirainterrogans persist indefinitely in the convoluted tubules of the kidney.
৫৬৫.
Cardiac output high, base deficit high and venous pressure low. Which type of shock is related to it-
  1. ক) Distributive shock
  2. খ) Endocrine shock
  3. গ) Obstructive shock
  4. ঘ) Cardiogenic shock
সঠিক উত্তর:
ক) Distributive shock
উত্তর
সঠিক উত্তর:
ক) Distributive shock
ব্যাখ্যা
In case of Distributive shock there is peripheral vasodilation & pooling of blood in periphery.
৫৬৬.
A positive tuberculin test signifies ... mediated immunity to mycobacterial antigen
  1. ক) T-cell
  2. খ) B-cell
  3. গ) NK cell
  4. ঘ) AP cell
সঠিক উত্তর:
ক) T-cell
উত্তর
সঠিক উত্তর:
ক) T-cell
ব্যাখ্যা
A positive tuberculin test signifies T-cell–mediated immunity to mycobacterial antigens but does not differentiate between infection and active disease.
৫৬৭.
Which is not the features of chronic liver disease -
  1. Loss of libido
  2. Spider telangiectecsia
  3. Ascities
  4. Cerebellar ataxia
সঠিক উত্তর:
Cerebellar ataxia
উত্তর
সঠিক উত্তর:
Cerebellar ataxia
ব্যাখ্যা
Explanation :
Clinical features of cirthosis of liver -
Jaundice
Ascitis
Hepatomegaly
Spider nevi
Gynaecomastia
Loss of libido
৫৬৮.
DNA -
  1. Composed of ribose suger and phosphate
  2. Nitrogenous base + sugar form neocleotide structure
  3. Neocleotide + phosphate group form neocleoside
  4. Cytosine is present in pyrimidine base
সঠিক উত্তর:
Cytosine is present in pyrimidine base
উত্তর
সঠিক উত্তর:
Cytosine is present in pyrimidine base
ব্যাখ্যা
Explanation :
DNA -
a polymer composed of two polynucleotide chains that coil around each other to form a double helix.
The polymer carries genetic instructions for the development, functioning and growth.
Each nucleotide is composed of one of four nitrogen-containing nucleobases (cytosine [C], guanine [G], adenine [A] or thymine [T]), a sugar called deoxyribose, and a phosphate group.
Purin base - Adenine and guanine
Pyrimidine base - Cytosine,Thymine,Uracil
৫৬৯.
Non hepatitic cause of hepatomegaly-
  1. ক) Budd chiari syndrome
  2. খ) CCF
  3. গ) Polycystic liver
  4. ঘ) Hydatid cyst
সঠিক উত্তর:
খ) CCF
উত্তর
সঠিক উত্তর:
খ) CCF
ব্যাখ্যা
CCF causes tender hepatomegaly
৫৭০.
Lactose fermentation does not occur in
  1. ক) Escherichia
  2. খ) Klebsiella
  3. গ) Enterobacter
  4. ঘ) Proteus
সঠিক উত্তর:
ঘ) Proteus
উত্তর
সঠিক উত্তর:
ঘ) Proteus
৫৭১.
Cardinal signs of right heart failure -
  1. Raised JVP
  2. Pulmonary oedema
  3. Cardiomegaly
  4. Plural effusion
সঠিক উত্তর:
Raised JVP
উত্তর
সঠিক উত্তর:
Raised JVP
ব্যাখ্যা
Explanation :
Cardinal signs of right heart failure  -
Raised JVP
Ascities
Pitting oedema
Hepatomegaly

Cardinal signs of left heart failure :
Bilateral basal crepitation
Gallop rhythm
Pulsus alternans
Orthopnea
৫৭২.
Parasites that are found in sputum are as follows:
  1. ক) Taenia solium
  2. খ) larva of ascariasis
  3. গ) Enterobius vermicularis
  4. ঘ) Balantidium coli
সঠিক উত্তর:
খ) larva of ascariasis
উত্তর
সঠিক উত্তর:
খ) larva of ascariasis
ব্যাখ্যা
Larva of Ascariasis can be found in sputum
৫৭৩.
Features of consolidation -
  1. Crepitation
  2. Diminised breath sound
  3. Diminished vocal resonance
  4. Mediastinal shifting
সঠিক উত্তর:
Crepitation
উত্তর
সঠিক উত্তর:
Crepitation
ব্যাখ্যা
Features of consolidation -
Crepitation
Bronchial breath sound
৫৭৪.
Ground glass cells are found in chronic infection with hepatitis
  1. ক) B
  2. খ) C
  3. গ) D
  4. ঘ) E
সঠিক উত্তর:
ক) B
উত্তর
সঠিক উত্তর:
ক) B
৫৭৫.
A 25-year-old man has a lifelong hemorrhagic diathesis. The PT and bleeding time are normal, but the APTT is prolonged. The most likely cause of the bleeding disorder is
  1. ক) factor VII deficiency
  2. খ) factor VIII deficiency
  3. গ) factor IX deficiency
  4. ঘ) von Willebrand disease
সঠিক উত্তর:
খ) factor VIII deficiency
উত্তর
সঠিক উত্তর:
খ) factor VIII deficiency
ব্যাখ্যা
In Haemophilia CT, APTT prolonged. BT, PT normal.
৫৭৬.
Crohns disease -
  1. Affect colon only
  2. Skip lesion
  3. Diffuse
  4. Limited to mucosa
সঠিক উত্তর:
Skip lesion
উত্তর
সঠিক উত্তর:
Skip lesion
ব্যাখ্যা
Explanation :
Crohns disease -
Bowel region : Ileum + colon
Distribution : Skip lesion
Stricture present
Transmural inflammation 
Lymphoid reaction : Marked
৫৭৭.
Normal value of serum potassium level -
  1. 3.5-5.5 mmol/l
  2. 98-110 mmol/l
  3. 135-145 mmol/l
  4. 285 -300 mmol /l
সঠিক উত্তর:
3.5-5.5 mmol/l
উত্তর
সঠিক উত্তর:
3.5-5.5 mmol/l
৫৭৮.
Disposable syringe is sterilized by -
  1. Ethylene oxide
  2. Formaldehyde
  3. Ultraviolet radiation
  4. Hexachloride
সঠিক উত্তর:
Ethylene oxide
উত্তর
সঠিক উত্তর:
Ethylene oxide
ব্যাখ্যা
Explanation :
Disposable syringe is sterilized by -
Ethylene oxide
Ionizing radiation. 
৫৭৯.
What is the most common cause of aortic aneurysm?
  1. ক) Hyperlipidaemia
  2. খ) Atherosclerosis
  3. গ) Hypertension
  4. ঘ) Diabetes Mellitus
সঠিক উত্তর:
খ) Atherosclerosis
উত্তর
সঠিক উত্তর:
খ) Atherosclerosis
ব্যাখ্যা
Reference: Davidson 23rd , Page : 505
৫৮০.
Which organism causes endocarditis following dental procedure?
  1. ক) S. aureus
  2. খ) S. epidermidis
  3. গ) Strep. Pyogenes
  4. ঘ) Viridians streptococcus
সঠিক উত্তর:
ঘ) Viridians streptococcus
উত্তর
সঠিক উত্তর:
ঘ) Viridians streptococcus
৫৮১.
Bilateral plantar extensor found in -
  1. Meningitis
  2. Peripheral neuropathy
  3. GBS
  4. Poliomyelitis
সঠিক উত্তর:
Meningitis
উত্তর
সঠিক উত্তর:
Meningitis
ব্যাখ্যা
Explanation -
Bilateral planter extension found in- structural lesions such as hemorrhage, brain and spinal cord tumors, and multiple sclerosis, and in abnormal metabolic states such as hypoglycemia, hypoxia, and anesthesia,infection - meningitis,encephalitis.
৫৮২.
Human papilloma virus is responsible for
  1. ক) Burkitt lymphoma
  2. খ) Kaposi sarcoma
  3. গ) Carcinoma of cervix
  4. ঘ) Merkel cell carcinoma
সঠিক উত্তর:
গ) Carcinoma of cervix
উত্তর
সঠিক উত্তর:
গ) Carcinoma of cervix
ব্যাখ্যা
Human papilloma virus is responsible for carcinoma of cervix
৫৮৩.
Component of innate immunity that create pore in microbial membrane
  1. ক) Lysozyme
  2. খ) Cilia
  3. গ) Phagocytes
  4. ঘ) Defensins
সঠিক উত্তর:
ঘ) Defensins
উত্তর
সঠিক উত্তর:
ঘ) Defensins
৫৮৪.
Which is not the feature of cerebellar lesion -
  1. Nystagmus
  2. Rigidity
  3. Intension tremor
  4. Poor performance in heel shin test
সঠিক উত্তর:
Rigidity
উত্তর
সঠিক উত্তর:
Rigidity
ব্যাখ্যা
Explanation -
 A mnemonic to remember some of the cerebellar signs is DANISH.
Dysdiadokinesia / dysmetria.
Ataxia.
Nystagmus.
Intention tremor.
Speech - slurred or scanning.
Hypotonia.
৫৮৫.
Hypertrophy of an organ-
  1. ক) Means increased size due to increased number of cells
  2. খ) Is always a pathological process
  3. গ) Is not seen where permanent cells make up the tissue
  4. ঘ) Is prone to ischaemia
সঠিক উত্তর:
ঘ) Is prone to ischaemia
উত্তর
সঠিক উত্তর:
ঘ) Is prone to ischaemia
ব্যাখ্যা
Ref. Robbins 9th p-34
৫৮৬.
CSF findings of pyogenic meningitis -
  1. Cell - Lymphocyte
  2. Low glucose level
  3. Normal protein count
  4. AFB may be found
সঠিক উত্তর:
Low glucose level
উত্তর
সঠিক উত্তর:
Low glucose level
৫৮৭.
Feature of anaplastic tumour is
  1. ক) Normal nuclear morphology
  2. খ) Pleomorphism
  3. গ) Typical mitotic figure
  4. ঘ) Normal polarity
সঠিক উত্তর:
খ) Pleomorphism
উত্তর
সঠিক উত্তর:
খ) Pleomorphism
ব্যাখ্যা
Feature of anaplastic tumour is pleomorphism
৫৮৮.
Temperature for autoclaving
  1. ক) 99
  2. খ) 101
  3. গ) 110
  4. ঘ) 121
সঠিক উত্তর:
ঘ) 121
উত্তর
সঠিক উত্তর:
ঘ) 121
৫৮৯.
Complement acting as opsonin is
  1. ক) C3b
  2. খ) C6а
  3. গ) C5b
  4. ঘ) C4b
সঠিক উত্তর:
ক) C3b
উত্তর
সঠিক উত্তর:
ক) C3b
ব্যাখ্যা
Complement acting as opsonin is C3b
৫৯০.
The most common stimulus for hypertrophy of muscle is
  1. ক) Increased workload
  2. খ) Decreased workload
  3. গ) Change in tissue type
  4. ঘ) Unexpected tissue death
সঠিক উত্তর:
ক) Increased workload
উত্তর
সঠিক উত্তর:
ক) Increased workload
ব্যাখ্যা

• Hypertrophy refers to an increase in the size of cells that result in an increase in the size of the affected organ.
• The hypertrophied organ has no new cells, just larger cells.
• The most common stimulus for hypertrophy of muscle is increased workload.
• Hypertrophy is the result of increased production of cellular proteins.

৫৯১.
IgM -
  1. Immunoglobulin of secondary immune response
  2. Cause type IV hypersensitivity
  3. Monomeric always
  4. Acts as a antigen receptor on B cell
সঠিক উত্তর:
Acts as a antigen receptor on B cell
উত্তর
সঠিক উত্তর:
Acts as a antigen receptor on B cell
ব্যাখ্যা
Explanation :
IgM -
Immunoglobulin of primary immune response 
Responsible for type II & Type III hypersensitivity
Acts a antigen receptor on B cell
Its a polymeric / pentameric form containing J chain
Highest molecular weight
৫৯২.
Which one is not urinary bladder tumor -
  1. ক) transitional cell tumor
  2. খ) squamous cell tumor
  3. গ) small cell tumor
  4. ঘ) Epithelial cell tumor
সঠিক উত্তর:
ঘ) Epithelial cell tumor
উত্তর
সঠিক উত্তর:
ঘ) Epithelial cell tumor
ব্যাখ্যা
Epithelial cell tumour is not urinary bladder tumour
৫৯৩.
Required plasma level(minimum) for development of gout
  1. ক) 5.8
  2. খ) 6.8
  3. গ) 7.8
  4. ঘ) 9.8
সঠিক উত্তর:
খ) 6.8
উত্তর
সঠিক উত্তর:
খ) 6.8
ব্যাখ্যা
• Hyperuricemia (plasma urate level above 6.8 mg/dL) is necessary, but not sufficient, for the development of gout.
৫৯৪.
Enzyme not involve in removal of free radical
  1. ক) Catalase
  2. খ) Dehydrogenase
  3. গ) Superoxidase dismutase
  4. ঘ) Glutathione peroxidase
সঠিক উত্তর:
খ) Dehydrogenase
উত্তর
সঠিক উত্তর:
খ) Dehydrogenase
ব্যাখ্যা
[Robbins 9th 48]
৫৯৫.
Most important mode of transmission in lepromatous leprosy
  1. ক) Skin contact
  2. খ) Nasal secretion
  3. গ) Fecal-oral
  4. ঘ) Blood borne
সঠিক উত্তর:
খ) Nasal secretion
উত্তর
সঠিক উত্তর:
খ) Nasal secretion
৫৯৬.
Cause of monoarthritis -
  1. Septic arthritis
  2. Reactive arthritis
  3. SLE
  4. Osteoarthritis
সঠিক উত্তর:
Septic arthritis
উত্তর
সঠিক উত্তর:
Septic arthritis
ব্যাখ্যা
Explanation -
Causes of acute monoarthritis :
Septic arthritis 
Gout
Pseudogout
Haemathroses
Trauma
Monoarticular presentation of polyarthritis
৫৯৭.
Features of progressive phase of shock -
  1. Lactic acidosis
  2. Release of Catecholamine
  3. Myocardial contraction
  4. Peripheral vasconstriction
সঠিক উত্তর:
Lactic acidosis
উত্তর
সঠিক উত্তর:
Lactic acidosis
ব্যাখ্যা
Explanation :
In progressive phase of shock -
Persistent oxygen deficit leads to intracellular aerobic respiration is replaced by anaerobic glycolysis with excessive production of lactic acid. The resultant metabolic lactic acidosis lowers the tissue pH, which blunts the vasomotor response; arterioles dilate, and blood begins to pool in the microcirculation.
Peripheral pooling not only worsens the cardiac output but also puts endothelial cells at risk for the development of anoxic injury with subsequent DIC.
With widespread tissue hypoxia, vital organs are affected and begin to fail.
৫৯৮.
Biochemical feature of gout is?
  1. ক) Hyperuricemia
  2. খ) Hypocalcaemia
  3. গ) Hypokalaemia
  4. ঘ) Hypernatraemia
সঠিক উত্তর:
ক) Hyperuricemia
উত্তর
সঠিক উত্তর:
ক) Hyperuricemia
ব্যাখ্যা
Explanation: Gout is marked by transient attacks of acute arthritis initiated by crystallization of monosodium urate within and around joints.
৫৯৯.
Which of the following is the vector of Plasmodia?
  1. ক) Culex quinquefasciatus
  2. খ) Aedes aegypti
  3. গ) Anopheles
  4. ঘ) Sand fly
সঠিক উত্তর:
গ) Anopheles
উত্তর
সঠিক উত্তর:
গ) Anopheles
ব্যাখ্যা
Explanation: The vector and definitive host for plasmodia is the female Anopheles mosquito
৬০০.
Lower urinary tract symptoms -
  1. Nocturia
  2. Loin pain
  3. Frequency and urgency
  4. Oliguria
সঠিক উত্তর:
Frequency and urgency
উত্তর
সঠিক উত্তর:
Frequency and urgency
ব্যাখ্যা
Explanation -
Lower urinary tract symptoms :
Dysuria,Frequency, Urgency 
Impaired urinary flow,Hesitency,Dribbling of urine,Incomplete emptying of bladder
Urinary retention
Incontinence