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Bleeding Disorders

মোট প্রশ্ন১৯এই পাতা১৯প্রতি পাতা১০০
প্রশ্ন দেখুনঅনুশীলন
ঘনত্ব
উত্তর
উত্তরিতবর্তমানপুনরায় দেখুনঅসম্পূর্ণ

Bleeding Disorders

PrepBank · পাতা ১ / ১ · ১–১৯ / ১৯

১.
Which is not a coagulation screening test?
  1. ক
    ক) Platelet count
  2. খ
    খ) BT
  3. গ
    গ) PT
  4. ঘ
    ঘ) APTT
ব্যাখ্যা
Explanation: coagulation screening tests are Platelet count, PT, APTT & Fibrinogen concentration
২.
Which of the following feature is absent in TTP?
  1. ক
    Thrombocytopenia
  2. খ
    Rena impairments
  3. গ
    Microcytic anaemia
  4. ঘ
    Fever
৩.
Causes of non thrombocytopenic purpura does not include
  1. ক
    ক) Vasculitis
  2. খ
    খ) IgA nephropathy
  3. গ
    গ) Senile purpura
  4. ঘ
    ঘ) Paraproteinaemias
ব্যাখ্যা
Ref: Davidson 23rd; P-928, box: 23.13
৪.
Dose of vit K in Haemorrhagic disease of the newborn?
  1. ক
    1 mg
  2. খ
    1 gm
  3. গ
    500mg
  4. ঘ
    0.1 mg
ব্যাখ্যা
Haemorrhagic disease of the newborn: Haemorrhagic disease of the newborn: enzyme-inducing antiepileptic drugs increase risk. Give IM vitamin K (1 mg) to the infant at birth.
৫.
Which of the following is not a Vitamin K dependant clotting factor?
  1. ক
    Factor II
  2. খ
    Factor V
  3. গ
    Factor IX
  4. ঘ
    Factor X
৬.
Haemophilia A occurs due to deficiency of
  1. ক
    ক) Factor VII
  2. খ
    খ) Factor VIII
  3. গ
    গ) Factor IX
  4. ঘ
    ঘ) Factor X
ব্যাখ্যা
Explanation: Factor VIII deficiency resulting in haemophilia A affects 1/10 000 individuals. It is the most common congenital coagulation factor deficiency
৭.
Which of the following conditions is not associated with ITP?
  1. ক
    HIV infection
  2. খ
    Pregnancy
  3. গ
    SLE
  4. ঘ
    T cell malignancy
ব্যাখ্যা
Page 981
৮.
Which of the subtype of vWD is AR
  1. ক
    1
  2. খ
    2A
  3. গ
    2B
  4. ঘ
    2N
৯.
Haemophilia
  1. ক
    ক) Autosomal dominant conditions
  2. খ
    খ) Autosomal recessive conditions
  3. গ
    গ) X-linked recessive conditions
  4. ঘ
    ঘ) X-linked dominant Condition
ব্যাখ্যা
Reference: Davidson 23rd, Box-3.4
১০.
The most common inherited hypercoagulable state is:
  1. ক
    Protein C deficiency
  2. খ
    Antithrombin deficiency
  3. গ
    Factor V Leiden mutation
  4. ঘ
    Prothrombin gene mutation
ব্যাখ্যা
Explanation: Factor V Leiden mutation is the most common inherited thrombophilia. Davidson explains that this mutation renders Factor V resistant to inactivation by activated protein C, leading to a prothrombotic state. Harrison discusses that individuals with Factor V Leiden have a higher risk of venous thromboembolism, particularly in the presence of additional risk factors like surgery or immobility.
১১.
Hemophilia A results from deficiency of
  1. ক
    ক) Factor-7
  2. খ
    খ) Factor-8
  3. গ
    গ) Factor-9
  4. ঘ
    ঘ) Factor-10
ব্যাখ্যা
Ref: Davidson 23rd; P-971
১২.
TTP is characterised by
  1. ক
    thrombocytopenia
  2. খ
    microangiopathic haemolytic anaemia
  3. গ
    neurological sequelae
  4. ঘ
    renal impairment
ব্যাখ্যা
TP is characterised by a pentad of findndings, although few patients have all five components:
 thrombocytopenia  microangiopathic haemolytic anaemia  neurological sequelae  fever  renal impairmen
১৩.
Coagulation screening tests excludes-
  1. ক
    Prothrombin time
  2. খ
    Clotting Time
  3. গ
    Platelet count
  4. ঘ
    Fibrinogen concentration
১৪.
Most common inherited bleeding disorder is?
  1. ক
    Haemophilia A
  2. খ
    Haemophilia B
  3. গ
    Von Willebrand disease
  4. ঘ
    Factor XIII deficiency
১৫.
Inhibition of post-translational modification is done by
  1. ক
    Warfarin
  2. খ
    Heparin
  3. গ
    PC
  4. ঘ
    Bivalirudin
ব্যাখ্যা
Innhibition of post-translational modification: Warfarin
১৬.
Von Willebrand factor is synthesised by
  1. ক
    ক) Plasma cell
  2. খ
    খ) Endothelial cells
  3. গ
    গ) Subendothelial collagen
  4. ঘ
    ঘ) Platelets
ব্যাখ্যা
Ref: Davidson 23rd; P-974
১৭.
Pooled immunoglobulin is used in
  1. ক
    Measles (exposed child with heart or lung disease)
  2. খ
    Hepatitis B
  3. গ
    Tetanus
  4. ঘ
    Rabies
১৮.
Which one is an example of mucosal bleeding?
  1. ক
    Retroperitoneal heamorrhage
  2. খ
    Fundal haemorrhage
  3. গ
    Intracranial haemorrhage
  4. ঘ
    Haemarthrosis
১৯.
Spontaneous bleeding in ITP usually occurs when platelet level is at least below
  1. ক
    ক) 20000
  2. খ
    খ) 30000
  3. গ
    গ) 40000
  4. ঘ
    ঘ) 50000
ব্যাখ্যা
Ref: Davidson 23rd; P-971