১.
Type of necrosis in abscess-
ব্যাখ্যা
[Robbins 9th 43]
PrepBank · বিষয়ভিত্তিক প্রশ্ন
Necrosis
Necrosis
PrepBank · পাতা ১ / ১ · ১–১৫ / ১৫
২.
Coagulative necrosis -
ব্যাখ্যা
Explanation :
Coagulative necrosis is a form of necrosis in which the architecture of dead tissue is preserved for a span of at least some days .
The affected tissue has a firm texture. Presumably, the injury denatures not only structural proteins but also enzymes and so blocks the proteolysis of the dead cells; as a result, intensely eosinophilic cells with indistinct or reddish nuclei may persist for days or weeks.
Ultimately, the necrotic cells are broken down by the action of lysosomal enzymes derived from infiltrating leukocytes, which also remove the debris of the dead cells by phagocytosis. Ischemia caused by obstruction in a vessel may lead to coagulative necrosis of the supplied tissue in all organs except the brain (see next paragraph for explanation).
A localized area of coagulative necrosis is called an infarct.
Coagulative necrosis is a form of necrosis in which the architecture of dead tissue is preserved for a span of at least some days .
The affected tissue has a firm texture. Presumably, the injury denatures not only structural proteins but also enzymes and so blocks the proteolysis of the dead cells; as a result, intensely eosinophilic cells with indistinct or reddish nuclei may persist for days or weeks.
Ultimately, the necrotic cells are broken down by the action of lysosomal enzymes derived from infiltrating leukocytes, which also remove the debris of the dead cells by phagocytosis. Ischemia caused by obstruction in a vessel may lead to coagulative necrosis of the supplied tissue in all organs except the brain (see next paragraph for explanation).
A localized area of coagulative necrosis is called an infarct.
৩.
Enzymatic fat necrosis occurs in
ব্যাখ্যা
Enzymatic fat necrosis occurs in pancreas
৪.
Ischemic necrosis of brain indicates which type of necrosis?
ব্যাখ্যা
• Coagulative: ischemic necrosis of heart, kidney, liver, adrenal gland & other solid organs; gumma of tertiary syphilis
• Liquefactive: boil, abscess & ischemic necrosis of brain
• Caseous: Granuloma of TB
• Fat: Enzymatic-pancreas, Traumatic- breast
• Fibrinioid: in collagen disease
৫.
Liquefactive necrosis is seen in -
ব্যাখ্যা
Liquefactive necrosis is seen in abscess
৬.
Site of avuscular necrosis -
ব্যাখ্যা
Explanation :
Avuscular necrosis seen in :
Head of femur
Talas
Scaphoid
Radiation therapy
Sickle cell crisis
Trauma
Tumor
Avuscular necrosis seen in :
Head of femur
Talas
Scaphoid
Radiation therapy
Sickle cell crisis
Trauma
Tumor
৭.
Myocardial infraction is an example of -
ব্যাখ্যা
Explanation :
Coagulative necrosis :
Occurs in solid organ except brain
Example - Infract of heart ( MI),Kidney,Spleen,Gumma of tertiary syphilis.
Coagulative necrosis :
Occurs in solid organ except brain
Example - Infract of heart ( MI),Kidney,Spleen,Gumma of tertiary syphilis.
৮.
Feature of irreversible cell injury -
ব্যাখ্যা
Explanation :
Features of irreversible cell injury -
Membrane injury
Intracellular release and activation of lysosomal enzyme
Increase calcium influx
Decreased basophilia
Phagocytosis.
Features of irreversible cell injury -
Membrane injury
Intracellular release and activation of lysosomal enzyme
Increase calcium influx
Decreased basophilia
Phagocytosis.
৯.
Site of traumatic fat necrosis -
ব্যাখ্যা
Explanation :
Site of traumatic fat necrosis -
Mostly breast
Then- salivary gland
Pancreas
Neonates after delivery.
Site of traumatic fat necrosis -
Mostly breast
Then- salivary gland
Pancreas
Neonates after delivery.
১০.
Not true about necrosis
১১.
Fibrinoid necrosis is seen in
ব্যাখ্যা
Fibrinoid necrosis is seen in SLE
১২.
Necroptosis false statement -
ব্যাখ্যা
Explanation -
Necroptosis -is a hybrid that shares aspects of both necrosis and apoptosis. Morphologically, and to some extent biochemically, it resembles necrosis, as both are characterized by loss of ATP, swelling of the cell and organelles, generation of reactive oxygen species (ROS), release of lysosomal enzymes, and ultimately rupture of the plasma membrane.
Mechanistically, it is triggered by signal transduction pathways that culminate in cell death, a feature similar to apoptosis. Because of these overlapping features, necroptosis is sometimes called programmed necrosis to distinguish it from forms of necrosis driven passively by toxic or ischemic injury to the cell.
Can occur both physiology and pathological condition.
Necroptosis -is a hybrid that shares aspects of both necrosis and apoptosis. Morphologically, and to some extent biochemically, it resembles necrosis, as both are characterized by loss of ATP, swelling of the cell and organelles, generation of reactive oxygen species (ROS), release of lysosomal enzymes, and ultimately rupture of the plasma membrane.
Mechanistically, it is triggered by signal transduction pathways that culminate in cell death, a feature similar to apoptosis. Because of these overlapping features, necroptosis is sometimes called programmed necrosis to distinguish it from forms of necrosis driven passively by toxic or ischemic injury to the cell.
Can occur both physiology and pathological condition.
১৩.
Which resembles necrosis morphologically & apoptosis mechanistically?
১৪.
Necroptosis occurs in-
ব্যাখ্যা
[Robbins 9th 59]
১৫.
Which of the following types of necrosis is most characteristic of abscess formation?
ব্যাখ্যা
Liquefactive necrosis occure in Pyogenic bacterial infection, brain hypoxia.