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PrepBank · বিষয়ভিত্তিক প্রশ্ন

Rheumatoid Arthritis

মোট প্রশ্ন১২এই পাতা১২প্রতি পাতা১০০
প্রশ্ন দেখুনঅনুশীলন
ঘনত্ব
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উত্তরিতবর্তমানপুনরায় দেখুনঅসম্পূর্ণ

Rheumatoid Arthritis

PrepBank · পাতা ১ / ১ · ১–১২ / ১২

১.
Visual function monitoring is required in which type of DMARDs
  1. ক
    ক) Sulfasalazine
  2. খ
    খ) Hydroxychloroquine
  3. গ
    গ) Mycophenolate mofetil
  4. ঘ
    ঘ) Azathioprine
ব্যাখ্যা
Ref: Davidson 23rd; P-1004 , box : 24.34
২.
Which of the following is not a risk factor for Felty syndrome?
  1. ক
    Age of onset 50-70 years
  2. খ
    Seronegative for rheumatoid factor
  3. গ
    Long standing rheumatoid arthritis
  4. ঘ
    Female sex
৩.
Which of the following DMARDs must be avoided in pregnancy?
  1. ক
    Sulfasalazine
  2. খ
    Azathioprine
  3. গ
    Methotrexate
  4. ঘ
    Hydroxichloroquin
৪.
Most Common Pulmonary feat in RA?
  1. ক
    Fibrosis
  2. খ
    Respiratory failure
  3. গ
    Sarcoisoisis
  4. ঘ
    Lung cancer
৫.
Investigation used to monitor disease activity of RA is-
  1. ক
    ক) Rheumatoid factor
  2. খ
    খ) Anti-citrullinated peptide antibodies
  3. গ
    গ) X-rays
  4. ঘ
    ঘ) Erythrocyte sedimentation rate
ব্যাখ্যা
Ref: Davidson 23rd; Box- 24.55
৬.
Visual function monitoring is required in case of which DMARD?
  1. ক
    Cyclophosphamide
  2. খ
    Hydroxychloroquine
  3. গ
    Leflunomide
  4. ঘ
    Methotrexate
৭.
‘Felty’s syndrome’ is associated with which of the following?
  1. ক
    ক) RA
  2. খ
    খ) SLE
  3. গ
    গ) OA
  4. ঘ
    ঘ) Gout
ব্যাখ্যা
Explanation: Felty’s syndrome is a rare complication of seropositive RA in which splenomegaly occurs in combination with neutropenia and thrombocytopenia
৮.
Which of the following is NOT a characteristic finding in rheumatoid arthritis?
  1. ক
    Symmetrical joint involvement
  2. খ
    Morning stiffness lasting >1 hour
  3. গ
    joint erosions on imaging
  4. ঘ
    Osteophyte formation
ব্যাখ্যা
Explanation: Osteophyte formation is characteristic of osteoarthritis, not rheumatoid arthritis. Davidson describes rheumatoid arthritis (RA) as a chronic autoimmune disease with symmetrical joint involvement, morning stiffness, and joint erosions visible on imaging. Harrison adds that RA is associated with systemic inflammation and can lead to joint deformity if untreated.
৯.
Highly specific for RA
  1. ক
    ক) ANA
  2. খ
    খ) RA
  3. গ
    গ) Anti CCP antibodies
  4. ঘ
    ঘ) Anti-ds DNA
ব্যাখ্যা
Anti-CCP antibodies are associated with rheumatoid arthritis (highly specific)
১০.
Caplan syndrome is a syndrome of ----------------------diameter rounded nodule
  1. ক
    0.5 cm
  2. খ
    0.5mm
  3. গ
    5mm
  4. ঘ
    0.5m
ব্যাখ্যা
Caplan syndrome describes the coexistence of rheumatoid arthritis and rounded fibrotic nodules 0.5–5 cm in diameter. They show pathological features similar to a rheumatoid nodule, including central necrosis, palisading histiocytes, and a peripheral rim of lymphocytes and plasma cells. This syndrome may also occur in other types of pneumoconiosis
১১.
Which one is the highly specific investigation for diagnosis Rheumatoid arthritis?
  1. ক
    ক) ANA
  2. খ
    খ) ANCA
  3. গ
    গ) ACPA
  4. ঘ
    ঘ) ESR
ব্যাখ্যা
Explanation: Tests for ACPA are positive in about 70% of cases and are highly specific for RA, occurring in many patients before clinical onset of the disease
১২.
Which of the following conditions is a major adverse effect of Ciclosporin?
  1. ক
    Nephrotoxicity
  2. খ
    Hepatotoxicity
  3. গ
    Gingival hypertrophy
  4. ঘ
    Leucopenia