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Hematology

মোট প্রশ্ন১৩৩এই পাতা৩২প্রতি পাতা১০০
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Hematology

PrepBank · পাতা / · ১০১১৩২ / ১৩৩

১০১.
Which one is the most common type of leukaemia?
  1. ক) ALL
  2. খ) CLL
  3. গ) AML
  4. ঘ) CML
সঠিক উত্তর:
খ) CLL
উত্তর
সঠিক উত্তর:
খ) CLL
ব্যাখ্যা
Explanation: Chronic lymphocytic leukaemia (CLL) is the most common variety of leukaemia
১০২.
Which of the following is a hallmarks of haemolysis?
  1. ক) ↓Haptoglobin
  2. খ) ↑Methaemalbumin
  3. গ) ↓Haemoglobin
  4. ঘ) Positive urinary haemosiderin
সঠিক উত্তর:
গ) ↓Haemoglobin
উত্তর
সঠিক উত্তর:
গ) ↓Haemoglobin
১০৩.
Example of direct thrombin inhibitor is?
  1. Abciximab
  2. Rivaroxaban
  3. Dabigatran
  4. Ticagrelor
সঠিক উত্তর:
Dabigatran
উত্তর
সঠিক উত্তর:
Dabigatran
১০৪.
Hodgkin’s lymphoma
  1. ক) Common in older age
  2. খ) More often restricted to lymph nodes in the neck
  3. গ) RS cell absent
  4. ঘ) Extra nodal involvement is common
সঠিক উত্তর:
খ) More often restricted to lymph nodes in the neck
উত্তর
সঠিক উত্তর:
খ) More often restricted to lymph nodes in the neck
১০৫.
Which one is increased or normal in anemia of chronic disease?
  1. ক) Ferritin
  2. খ) Iron
  3. গ) TIBC
  4. ঘ) Transferrin saturation
সঠিক উত্তর:
ক) Ferritin
উত্তর
সঠিক উত্তর:
ক) Ferritin
১০৬.
Most common inherited bleeding disorder is?
  1. Haemophilia A
  2. Haemophilia B
  3. Von Willebrand disease
  4. Factor XIII deficiency
সঠিক উত্তর:
Von Willebrand disease
উত্তর
সঠিক উত্তর:
Von Willebrand disease
১০৭.
Bone Marrow Aspiration Needle parts
  1. Trocar.
  2. Cannula
  3. Adjustable side guard
  4. All
সঠিক উত্তর:
All
উত্তর
সঠিক উত্তর:
All
ব্যাখ্যা
Bone Marrow Aspiration Needle (Metal, Salah type) – 14, 16, 18G, 5 Cm long
Trocar.
Cannula.
Adjustable side guard: Helps in adjusting the depth of penetration of the needle.
১০৮.
Which type of leukaemia is mainly found in child age group?
  1. ক) acute lymphoblastic leukaemia (ALL)
  2. খ) acute myeloid leukaemia (AML)
  3. গ) chronic lymphocytic leukaemia (CLL)
  4. ঘ) chronic myeloid leukaemia (CML)
সঠিক উত্তর:
ক) acute lymphoblastic leukaemia (ALL)
উত্তর
সঠিক উত্তর:
ক) acute lymphoblastic leukaemia (ALL)
ব্যাখ্যা
Explanation: Acute lymphoblastic leukaemia shows a peak of incidence in children aged 1–5 years.
১০৯.
In lymphoma how many lesion in CT scan findings is found?
  1. 1
  2. 2
  3. 3
  4. 4
সঠিক উত্তর:
1
উত্তর
সঠিক উত্তর:
1
১১০.
Incase of blood group ‘O’, which antibodies present in Plasma?
  1. ক) Anti-A
  2. খ) Anti-B
  3. গ) Anti-A and anti-B
  4. ঘ) None
সঠিক উত্তর:
গ) Anti-A and anti-B
উত্তর
সঠিক উত্তর:
গ) Anti-A and anti-B
১১১.
Cellular immunity is mediated by which of the following?
  1. ক) Neutrophil
  2. খ) Basophil
  3. গ) T lymphocyte
  4. ঘ) B lymphocyte
সঠিক উত্তর:
গ) T lymphocyte
উত্তর
সঠিক উত্তর:
গ) T lymphocyte
ব্যাখ্যা
Explanation: Cellular immunity is mediated by T lymphocytes
১১২.
Inhibition of post-translational modification is done by
  1. Warfarin
  2. Heparin
  3. PC
  4. Bivalirudin
সঠিক উত্তর:
Warfarin
উত্তর
সঠিক উত্তর:
Warfarin
ব্যাখ্যা
Innhibition of post-translational modification: Warfarin
১১৩.
Which one is a primary lymphoid organ?
  1. ক) Thymus
  2. খ) Spleen
  3. গ) lymph nodes
  4. ঘ) and mucosa-associated lymphoid tissue
সঠিক উত্তর:
ক) Thymus
উত্তর
সঠিক উত্তর:
ক) Thymus
১১৪.
All of the following are causes of secondary aplastic anemia except-
  1. Penicillin
  2. Penicillamine
  3. Azathioprine
  4. Carbimazole
সঠিক উত্তর:
Penicillin
উত্তর
সঠিক উত্তর:
Penicillin
১১৫.
In iron deficiency anaemia, there is-
  1. Decreased soluble transferrin receptor
  2. Increased transferrin saturation
  3. Increased TIBC
  4. Normal ferritin
সঠিক উত্তর:
Increased TIBC
উত্তর
সঠিক উত্তর:
Increased TIBC
১১৬.
Von Willebrand factor is synthesised by
  1. ক) Plasma cell
  2. খ) Endothelial cells
  3. গ) Subendothelial collagen
  4. ঘ) Platelets
সঠিক উত্তর:
খ) Endothelial cells
উত্তর
সঠিক উত্তর:
খ) Endothelial cells
ব্যাখ্যা
Ref: Davidson 23rd; P-974
১১৭.
Basophilic stippling is a feature of
  1. ক) Hemolysis
  2. খ) Hemorrhage
  3. গ) Lead poisoning
  4. ঘ) DIC
সঠিক উত্তর:
গ) Lead poisoning
উত্তর
সঠিক উত্তর:
গ) Lead poisoning
১১৮.
Pooled immunoglobulin is used in
  1. Measles (exposed child with heart or lung disease)
  2. Hepatitis B
  3. Tetanus
  4. Rabies
সঠিক উত্তর:
Measles (exposed child with heart or lung disease)
উত্তর
সঠিক উত্তর:
Measles (exposed child with heart or lung disease)
১১৯.
Which one of the following doesn’t cause eosinophilia?
  1. Parasitic infection
  2. Hay fever
  3. Salmonella
  4. Acute myeloid leukaemia
সঠিক উত্তর:
Salmonella
উত্তর
সঠিক উত্তর:
Salmonella
১২০.
Histiocytic disorders is
  1. Langerhans cell histiocytosis (LCH
  2. Cutaneous and mucocutaneous histiocytosis
  3. Malignant histiocytosis (M)
  4. All
সঠিক উত্তর:
All
উত্তর
সঠিক উত্তর:
All
১২১.
Which immunoglobulin is responsible for mucosal defence?
  1. IgG
  2. IgA
  3. IgM
  4. IgE
সঠিক উত্তর:
IgA
উত্তর
সঠিক উত্তর:
IgA
১২২.
Most common cause of iron deficiency in old age is-
  1. Pernicious anaemia
  2. Anaemia of chronic disease
  3. Gastrointestinal blood loss
  4. Malignancy
সঠিক উত্তর:
Gastrointestinal blood loss
উত্তর
সঠিক উত্তর:
Gastrointestinal blood loss
১২৩.
Most common type of hodgkin lymphoma is?
  1. ক) Nodular sclerosing
  2. খ) Mixed cellularity
  3. গ) Lymphocyte-rich
  4. ঘ) Lymphocyte-depleted
সঠিক উত্তর:
ক) Nodular sclerosing
উত্তর
সঠিক উত্তর:
ক) Nodular sclerosing
১২৪.
Abnormal ribosomal RNA that appear as blue dots are found in-
  1. Sickle cell disease
  2. Post splenectomy
  3. Lead poisoning
  4. Haemoglobin C disease
সঠিক উত্তর:
Lead poisoning
উত্তর
সঠিক উত্তর:
Lead poisoning
১২৫.
A 30-year-old woman presents with fatigue, easy bruising, and frequent nosebleeds. Laboratory tests show pancytopenia, and a bone marrow biopsy reveals hypocellularity. What is the most likely diagnosis?
  1. Aplastic anemia
  2. Acute myeloid leukemia (AML)
  3. Immune thrombocytopenic purpura (ITP)
  4. Myelodysplastic syndrome (MDS)
সঠিক উত্তর:
Aplastic anemia
উত্তর
সঠিক উত্তর:
Aplastic anemia
ব্যাখ্যা
Stem Breakdown:

Fatigue, easy bruising, and frequent nosebleeds: These symptoms suggest bone marrow failure, leading to anaemia (fatigue), thrombocytopenia (bruising, nosebleeds), and possibly leukopenia.
Pancytopenia and hypocellular bone marrow: Pancytopenia (low red cells, white cells, and platelets) with a hypocellular bone marrow is characteristic of aplastic anaemia.
Option Analysis:

A) Aplastic anaemia: This is the correct diagnosis. Davidson and Harrison describe aplastic anaemia as a condition in which the bone marrow fails to produce sufficient blood cells, leading to pancytopenia. The bone marrow is hypocellular (decreased cell production), and the condition can be caused by autoimmune factors, infections, or exposure to toxins.
B) Acute myeloid leukaemia (AML): AML presents with pancytopenia and blasts in the blood or bone marrow, but it is associated with hypercellular bone marrow filled with malignant cells, not hypocellularity.
C) Immune thrombocytopenic purpura (ITP): ITP causes isolated thrombocytopenia (low platelet count), leading to easy bruising and bleeding. However, it does not cause anaemia or leukopenia, and the bone marrow is typically normal or shows increased megakaryocytes.
D) Myelodysplastic syndrome (MDS): MDS can cause pancytopenia, but the bone marrow in MDS is usually hypercellular with abnormal maturation of blood cells, not hypocellular.
১২৬.
Which is not a phagocytic cell?
  1. ক) Neutrophils
  2. খ) Lymphocyte
  3. গ) monocytes
  4. ঘ) Macrophages
সঠিক উত্তর:
খ) Lymphocyte
উত্তর
সঠিক উত্তর:
খ) Lymphocyte
ব্যাখ্যা
Explanation: phagocytic cell includes neutrophils, monocytes and macrophages
১২৭.
Which one is an example of mucosal bleeding?
  1. Retroperitoneal heamorrhage
  2. Fundal haemorrhage
  3. Intracranial haemorrhage
  4. Haemarthrosis
সঠিক উত্তর:
Fundal haemorrhage
উত্তর
সঠিক উত্তর:
Fundal haemorrhage
১২৮.
Indirect Coombs test is used to detect-
  1. Autoimmune haemolytic anaemia
  2. Antibody screen in pre transfusion testing
  3. Haemolytic disease of newborn
  4. Transfusion reactions
সঠিক উত্তর:
Antibody screen in pre transfusion testing
উত্তর
সঠিক উত্তর:
Antibody screen in pre transfusion testing
ব্যাখ্যা
Davidson 24th Ed, Page 957

১২৯.
Which one is the Iron Chelating agent?
  1. ক) Hydroxocobalamin
  2. খ) DMSA
  3. গ) Desferrioxamine
  4. ঘ) Dicobalt edetate
সঠিক উত্তর:
গ) Desferrioxamine
উত্তর
সঠিক উত্তর:
গ) Desferrioxamine
১৩০.
Which one of the following is multinucleated cells of haematopoietic origin?
  1. ক) Osteoblasts
  2. খ) Osteoclasts
  3. গ) Osteocytes
  4. ঘ) Bone marrow stromal cells
সঠিক উত্তর:
খ) Osteoclasts
উত্তর
সঠিক উত্তর:
খ) Osteoclasts
ব্যাখ্যা
Explanation: Osteoclasts are multinucleated cells of haematopoietic origin, responsible for bone resorption. Osteoblasts are mononuclear cells
১৩১.
Spontaneous bleeding in ITP usually occurs when platelet level is at least below
  1. ক) 20000
  2. খ) 30000
  3. গ) 40000
  4. ঘ) 50000
সঠিক উত্তর:
ক) 20000
উত্তর
সঠিক উত্তর:
ক) 20000
ব্যাখ্যা
Ref: Davidson 23rd; P-971
১৩২.
Which of the following is the primary treatment for venous thromboembolism (VTE)?
  1. Aspirin
  2. Heparin
  3. Warfarin
  4. Clopidogrel
সঠিক উত্তর:
Heparin
উত্তর
সঠিক উত্তর:
Heparin
ব্যাখ্যা
Explanation: Heparin, particularly low-molecular-weight heparin (LMWH), is the primary treatment for venous thromboembolism (VTE). Davidson explains that heparin acts by potentiating antithrombin III, leading to the inhibition of thrombin and factor Xa. Harrison adds that anticoagulation is continued with warfarin or direct oral anticoagulants (DOACs) for long-term management to prevent recurrence.