১০১.
Which one is the most common type of leukaemia?
ব্যাখ্যা
Explanation: Chronic lymphocytic leukaemia (CLL) is the most common variety of leukaemia
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Hematology
Hematology
PrepBank · পাতা ২ / ২ · ১০১–১৩২ / ১৩৩
১০২.
Which of the following is a hallmarks of haemolysis?
১০৩.
Example of direct thrombin inhibitor is?
১০৪.
Hodgkin’s lymphoma
১০৫.
Which one is increased or normal in anemia of chronic disease?
১০৬.
Most common inherited bleeding disorder is?
১০৭.
Bone Marrow Aspiration Needle parts
ব্যাখ্যা
Bone Marrow Aspiration Needle (Metal, Salah type) – 14, 16, 18G, 5 Cm long
Trocar.
Cannula.
Adjustable side guard: Helps in adjusting the depth of penetration of the needle.
১০৮.
Which type of leukaemia is mainly found in child age group?
ব্যাখ্যা
Explanation: Acute lymphoblastic leukaemia shows a peak of incidence in children aged 1–5 years.
১০৯.
In lymphoma how many lesion in CT scan findings is found?
১১০.
Incase of blood group ‘O’, which antibodies present in Plasma?
১১১.
Cellular immunity is mediated by which of the following?
ব্যাখ্যা
Explanation: Cellular immunity is mediated by T lymphocytes
১১২.
Inhibition of post-translational modification is done by
ব্যাখ্যা
Innhibition of post-translational modification: Warfarin
১১৩.
Which one is a primary lymphoid organ?
১১৪.
All of the following are causes of secondary aplastic anemia except-
১১৫.
In iron deficiency anaemia, there is-
১১৬.
Von Willebrand factor is synthesised by
ব্যাখ্যা
Ref: Davidson 23rd; P-974
১১৭.
Basophilic stippling is a feature of
১১৮.
Pooled immunoglobulin is used in
১১৯.
Which one of the following doesn’t cause eosinophilia?
১২০.
Histiocytic disorders is
১২১.
Which immunoglobulin is responsible for mucosal defence?
১২২.
Most common cause of iron deficiency in old age is-
১২৩.
Most common type of hodgkin lymphoma is?
১২৪.
Abnormal ribosomal RNA that appear as blue dots are found in-
১২৫.
A 30-year-old woman presents with fatigue, easy bruising, and frequent nosebleeds. Laboratory tests show pancytopenia, and a bone marrow biopsy reveals hypocellularity. What is the most likely diagnosis?
ব্যাখ্যা
Stem Breakdown:
Fatigue, easy bruising, and frequent nosebleeds: These symptoms suggest bone marrow failure, leading to anaemia (fatigue), thrombocytopenia (bruising, nosebleeds), and possibly leukopenia.
Pancytopenia and hypocellular bone marrow: Pancytopenia (low red cells, white cells, and platelets) with a hypocellular bone marrow is characteristic of aplastic anaemia.
Option Analysis:
A) Aplastic anaemia: This is the correct diagnosis. Davidson and Harrison describe aplastic anaemia as a condition in which the bone marrow fails to produce sufficient blood cells, leading to pancytopenia. The bone marrow is hypocellular (decreased cell production), and the condition can be caused by autoimmune factors, infections, or exposure to toxins.
B) Acute myeloid leukaemia (AML): AML presents with pancytopenia and blasts in the blood or bone marrow, but it is associated with hypercellular bone marrow filled with malignant cells, not hypocellularity.
C) Immune thrombocytopenic purpura (ITP): ITP causes isolated thrombocytopenia (low platelet count), leading to easy bruising and bleeding. However, it does not cause anaemia or leukopenia, and the bone marrow is typically normal or shows increased megakaryocytes.
D) Myelodysplastic syndrome (MDS): MDS can cause pancytopenia, but the bone marrow in MDS is usually hypercellular with abnormal maturation of blood cells, not hypocellular.
Fatigue, easy bruising, and frequent nosebleeds: These symptoms suggest bone marrow failure, leading to anaemia (fatigue), thrombocytopenia (bruising, nosebleeds), and possibly leukopenia.
Pancytopenia and hypocellular bone marrow: Pancytopenia (low red cells, white cells, and platelets) with a hypocellular bone marrow is characteristic of aplastic anaemia.
Option Analysis:
A) Aplastic anaemia: This is the correct diagnosis. Davidson and Harrison describe aplastic anaemia as a condition in which the bone marrow fails to produce sufficient blood cells, leading to pancytopenia. The bone marrow is hypocellular (decreased cell production), and the condition can be caused by autoimmune factors, infections, or exposure to toxins.
B) Acute myeloid leukaemia (AML): AML presents with pancytopenia and blasts in the blood or bone marrow, but it is associated with hypercellular bone marrow filled with malignant cells, not hypocellularity.
C) Immune thrombocytopenic purpura (ITP): ITP causes isolated thrombocytopenia (low platelet count), leading to easy bruising and bleeding. However, it does not cause anaemia or leukopenia, and the bone marrow is typically normal or shows increased megakaryocytes.
D) Myelodysplastic syndrome (MDS): MDS can cause pancytopenia, but the bone marrow in MDS is usually hypercellular with abnormal maturation of blood cells, not hypocellular.
১২৬.
Which is not a phagocytic cell?
ব্যাখ্যা
Explanation: phagocytic cell includes neutrophils, monocytes and macrophages
১২৭.
Which one is an example of mucosal bleeding?
১২৮.
Indirect Coombs test is used to detect-
ব্যাখ্যা
Davidson 24th Ed, Page 957
১২৯.
Which one is the Iron Chelating agent?
১৩০.
Which one of the following is multinucleated cells of haematopoietic origin?
ব্যাখ্যা
Explanation: Osteoclasts are multinucleated cells of haematopoietic origin, responsible for bone resorption. Osteoblasts are mononuclear cells
১৩১.
Spontaneous bleeding in ITP usually occurs when platelet level is at least below
ব্যাখ্যা
Ref: Davidson 23rd; P-971
১৩২.
Which of the following is the primary treatment for venous thromboembolism (VTE)?
ব্যাখ্যা
Explanation: Heparin, particularly low-molecular-weight heparin (LMWH), is the primary treatment for venous thromboembolism (VTE). Davidson explains that heparin acts by potentiating antithrombin III, leading to the inhibition of thrombin and factor Xa. Harrison adds that anticoagulation is continued with warfarin or direct oral anticoagulants (DOACs) for long-term management to prevent recurrence.