১.
Gout is an adverse effect of
সঠিক উত্তর: খ
খ) Pyrazinamide
উত্তর
সঠিক উত্তর: খ
খ) Pyrazinamide
ব্যাখ্যা
Reference: Davidson 23rd; P-593
PrepBank · বিষয়ভিত্তিক প্রশ্ন
Rational Antibiotic Use & Side-Effects
Rational Antibiotic Use & Side-Effects
PrepBank · পাতা ১ / ১ · ১–১৮ / ১৮
খ
২.
Retrobulbar neuritis is a major adverse reaction observed in therapy with
সঠিক উত্তর: খ
খ) Ethambutol
উত্তর
সঠিক উত্তর: খ
খ) Ethambutol
ব্যাখ্যা
Reference: Davidson 23rd; P-593
৩.
Adverse effect of Quinolones on ECG related to
সঠিক উত্তর: ঘ
QT
উত্তর
সঠিক উত্তর: ঘ
QT
ব্যাখ্যা
Adverse effects Gastrointestinal side-effects in 1%–5%.
Rare skin reactions (phototoxicity). Tendinitis and Achilles tendon rupture, especially in older people. Central nervous system effects (delirium, tremor, dizziness and occasional seizures in 5%–12%), especially in older people.
Reduces clearance of xanthines and theophyllines, potentially inducing insomnia and increased seizure potential.
Prolongation of QT interval on ECG, cardiac arrhythmias. Ciprooxacin use is associated with acquisition of MRSA and strains of C. difcile
Rare skin reactions (phototoxicity). Tendinitis and Achilles tendon rupture, especially in older people. Central nervous system effects (delirium, tremor, dizziness and occasional seizures in 5%–12%), especially in older people.
Reduces clearance of xanthines and theophyllines, potentially inducing insomnia and increased seizure potential.
Prolongation of QT interval on ECG, cardiac arrhythmias. Ciprooxacin use is associated with acquisition of MRSA and strains of C. difcile
৪.
Antimicrobials causing pulmonary eosinophilia except
সঠিক উত্তর: গ
গ) Erythromycin
উত্তর
সঠিক উত্তর: গ
গ) Erythromycin
ব্যাখ্যা
Reference: Davidson 23rd; P-612
৫.
mRNA synthesis inhibitor
সঠিক উত্তর: ঘ
ঘ) Rifampicin
উত্তর
সঠিক উত্তর: ঘ
ঘ) Rifampicin
৬.
Antibiotic of choice in septic arthritis
সঠিক উত্তর: গ
গ) Flucloxacillin
উত্তর
সঠিক উত্তর: গ
গ) Flucloxacillin
ব্যাখ্যা
Ref: Davidson 23rd; P-1020
৭.
Regarding Paromomycin which is not correct?
সঠিক উত্তর: খ
It is significantly absorbed when administered orally
উত্তর
সঠিক উত্তর: খ
It is significantly absorbed when administered orally
ব্যাখ্যা
Paromomycin is an aminoglycoside that is used to treat visceral leishmaniasis and intestinal amoebiasis. It is not significantly absorbed when administered orally, and is therefore given orally for intestinal amoebiasis and by intramuscular injection for leishmaniasis. It showed early promise in the treatment of HIV-associated cryptosporidiosis but subsequent trials have demonstrated that this effect is marginal at best.
৮.
Common side effect of H. pylori eradication therapy
সঠিক উত্তর: ক
ক) Diarrhoea
উত্তর
সঠিক উত্তর: ক
ক) Diarrhoea
ব্যাখ্যা
Reference: Davidson 23rd; P-800
৯.
Hemolytic anemia is a side effect of
সঠিক উত্তর: ক
Rifampicin
উত্তর
সঠিক উত্তর: ক
Rifampicin
১০.
Which anti-TB drug causes Gout?
সঠিক উত্তর: গ
গ) Pyrazinamide
উত্তর
সঠিক উত্তর: গ
গ) Pyrazinamide
ব্যাখ্যা
Drugs causes gout are: Thiazide and loop diuretics, Low-dose aspirin, Ciclosporin & Pyrazinamide
১১.
Type 3 hypersensitivity
সঠিক উত্তর: গ
গ) Serum sickness
উত্তর
সঠিক উত্তর: গ
গ) Serum sickness
১২.
Antidote for Isoniazid toxicity is-
সঠিক উত্তর: গ
Pyridoxine
উত্তর
সঠিক উত্তর: গ
Pyridoxine
১৩.
Antimicrobials causing pulmonary eosinophilia except
সঠিক উত্তর: ঘ
ঘ) Erythromycin
উত্তর
সঠিক উত্তর: ঘ
ঘ) Erythromycin
ব্যাখ্যা
Reference: Davidson 23rd; P-612
১৪.
Which anti-TB drug cause Hyperuricaemia?
সঠিক উত্তর: গ
গ) Pyrazinamide
উত্তর
সঠিক উত্তর: গ
গ) Pyrazinamide
ব্যাখ্যা
Explanation: please see question 45
১৫.
First-choice oral antibiotic for non-severe symptoms or signs and not at higher risk of resistance
সঠিক উত্তর: ক
Co-amoxiclav
উত্তর
সঠিক উত্তর: ক
Co-amoxiclav
১৬.
54-year-old woman presents to the emergency department with fevers and a sore throat. She has recently been diagnosed with left-sided breast cancer and associated axillary lymph node disease. Twelve days ago she received her first cycle of neoadjuvant cytotoxic chemotherapy (5-uorouracil, epirubicin and cyclophosphamide). On clinical examination, her temperature is 38.3°C; she appears dehydrated and there is evidence of oral candidiasis. An intravenous catheter is placed and bloods, including blood cultures, taken. What is the most appropriate next step in this patient’s care?
সঠিক উত্তর: ঘ
Start high-dose broad-spectrum intravenous antibiotic therapy immediately
উত্তর
সঠিক উত্তর: ঘ
Start high-dose broad-spectrum intravenous antibiotic therapy immediately
ব্যাখ্যা
The clinical features here are of fever in a patient at high risk of neutropenia. This is an oncological emergency. Patients are at risk of neutropenia at any point during their systemic anti-cancer therapy treatment cycle, with the highest risk typically 10–14 days after a treatment. In patients with potential neutropenic sepsis high-dose broad spectrum intravenous antibiotics should be commenced, ideally within 1 hour of admission, without awaiting test results. In this should not delay the first dose of antibiotic therapy. Test results may later inform changes to antimicrobial therapy and its duration.
১৭.
Antimicrobials causing pulmonary eosinophilia except
সঠিক উত্তর: ঘ
Erythromycin
উত্তর
সঠিক উত্তর: ঘ
Erythromycin
ব্যাখ্যা
Reference: Davidson 23rd; P-612
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
১৮.
Which anti-TB drug causes hyperuricaemia?
সঠিক উত্তর: গ
গ) Pyrazinamide
উত্তর
সঠিক উত্তর: গ
গ) Pyrazinamide