Neuropathies

Davidson 23rd; P-1082

Reference: Davidson 23rd; P-758

Explanation: Campylobacter species have been linked to GBS & post infectious reactive arthritis.

Extension of pituitary tumor into avernous sinus with subsequent compression of the 3rd, 4th or 6th  cranial nerve may cause diplopia and strabismus, but in anterior pituitary  tumours this is an unusual presentation.

Davidson 24th-695

Reference: Davidson 23rd, Box-25.87

Finger clubbing is due to overgrowth of soft tissue in the terminal phalanx, which increases the lateral and longitudinal curvature of the nail (see Fig. 3.8), raising the nail bed off the underlying bone. It is palpable as a boggy fluctuation of the nail when pressure is applied just proximal to the nail 

The most common respiratory causes of clubbing are chronic suppurative lung disease (such as bronchiectasis), lung cancer and pulmonary fibrosis. An additional rare complication of lung cancer is hypertrophic pulmonary osteoarthropathy, in which painful, tender swelling of
the wrists and ankles accompanies pronounced finger clubbing. X-rays of the distal forearm and lower legs show subperiosteal
new bone formation overlying the cortex of the long bones.
Other important signs of respiratory disease in the hands include:
•     cyanosis
•     tar staining of fingers from tobacco use (Fig. 5.8)
•     small-muscle wasting (see Fig. 13.22), which may indicate
T1 root damage by an apical lung tumour
•     rarely, yellow–brown discoloration of nails in yellow nail
syndrome

Sensory: 1, 2, 8
Motor: 3, 4, 6, 11, 12
Mixed: 5, 7, 9, 10

Reference: Davidson 23rd, Page: 760 , Box : 20.41

Reference: Davidson 23rd, Page: 1141
Explanation: The most evident symptom is fatigable muscle weakness. Worsening of symptoms towards the end of the day or following exercise is characteristic.