১.
Followings are the major symptoms of Crohn’s disease, excludes..
ব্যাখ্যা
Explanation: The major symptoms are abdominal pain, diarrhoea and weight loss. Ddiarrhea, which is usually watery and does not contain blood or mucus.
PrepBank · বিষয়ভিত্তিক প্রশ্ন
Inflammatory Bowel Disease
Inflammatory Bowel Disease
PrepBank · পাতা ১ / ১ · ১–২৮ / ২৮
২.
Which can protect ulcerative colitis?
ব্যাখ্যা
Reference: Davidson 23rd; P-814
৩.
Most common disease distribution in ulcerative colitis is?
৪.
Left iliac fossa mass commonly indicates all of the following excepts
৫.
Test to detect mucosal inflammation-
৬.
Which of the following is true for Ulcerative colitis?
৭.
Which is not a histological features of Ulcerative colitis?
ব্যাখ্যা
Explanation: histological features of Ulcerative colitis are: Inflammation limited to mucosa, crypt distortion, cryptitis, crypt abscesses, loss of goblet cells,
৮.
Both ESR & CRP raised in which of the following condition?
ব্যাখ্যা
Reference: Davidson 23rd, Box-4.4
৯.
Faecal calprotectin is tested to detect
ব্যাখ্যা
Reference: Davidson 23rd; P-777
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
১০.
Which drug is safe in pregnancy for the treatment of inflammatory bowel disease?
১১.
The major symptom of Crohn’s disease
ব্যাখ্যা
Reference: Davidson 23rd; P-816
১২.
A 38-year-old man presents with abdominal pain, bloody diarrhea, and tenesmus (painful straining). Colonoscopy reveals continuous inflammation from the rectum to the sigmoid colon. What is the most likely diagnosis?
ব্যাখ্যা
Stem Breakdown:
Abdominal pain, bloody diarrhoea, and tenesmus: These are classic symptoms of ulcerative colitis (UC), which is an inflammatory bowel disease affecting the colon.
Continuous inflammation from the rectum to the sigmoid colon: UC is characterised by continuous inflammation starting in the rectum and extending proximally, often limited to the colon.
Option Analysis:
A) Ulcerative colitis: This is the correct diagnosis. Davidson and Harrison describe ulcerative colitis as a chronic inflammatory condition of the colon characterised by continuous inflammation, starting at the rectum and extending proximally. Bloody diarrhoea, abdominal pain, and tenses are hallmark symptoms. UC is often limited to the mucosa and submucosa of the colon, distinguishing it from Crohn's disease.
B) Crohn’s disease: Crohn's disease can affect any part of the gastrointestinal tract and is characterised by "skip lesions" (areas of normal bowel between inflamed segments). It also often involves transmural (full-thickness) inflammation, which can lead to complications like fistulas and strictures. The continuous inflammation seen in this patient is more typical of UC.
C) Irritable bowel syndrome (IBS): IBS causes abdominal pain and altered bowel habits (diarrhoea or constipation), but it does not cause bloody diarrhoea or visible inflammation on colonoscopy. IBS is a functional gastrointestinal disorder, not an inflammatory disease.
D) Diverticulitis: Diverticulitis presents with localised left lower quadrant pain, fever, and leukocytosis, typically without bloody diarrhoea or continuous inflammation on colonoscopy.
১৩.
Histological feature of Crohn’s disease is?
১৪.
Which information is true regarding Crohn’s disease?
১৫.
A 59-year-old woman is seen in the emergency department with a 2-day history of severe diarrhoea. She has had 10 loose stools today, the most recent of which have been bloody and associated with crampy abdominal pain. Her past medical history includes metastatic melanoma and she had her fourth cycle of ipilimumab and nivolumab therapy 20 days ago. At the time of her treatment she was constipated and the outpatient systemic anti-cancer therapy unit doctor prescribed her a macrogol laxative. She notes that the evening prior to the diarrhoea starting she had reheated some leftover rice for her supper. What is the most important likely diagnosis?
ব্যাখ্যা
Immune-related adverse events should be considered in all patients who present acutely unwell following immunotherapy treatments for cancer. Although the other options are on the differential diagnosis list, severe IRAEs are oncological emergencies, and prompt recognition and management are vital. This is a grade 3 colitis and should be treated with IV methylprednisolone in the first instance. Investigations such as bloods, stool samples, radiological imaging and flexible sigmoidoscopy or colonoscopy are also appropriate.
১৬.
In a case of Crohn's disease, which area is commonly affected?
ব্যাখ্যা
Explanation: The area most commonly affected is the Ileal or ileocolonic region
১৭.
Which of the following feature is reralted to the activity of inflammatory bowel disease?
ব্যাখ্যা
Reference: Davidson 23rd Fig. 21.52
১৮.
Which of the following drugs is safe for treatment of IBD during pregnancy?
১৯.
Which can involve any part of the GIT from mouth to anus?
ব্যাখ্যা
Reference: Davidson 23rd; P-813
২০.
Which disease can involve any part of GIT from mouth to anus?
ব্যাখ্যা
Reference: Davidson 23rd; P-813
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
২১.
Which disease is greatly associated with Ulcerative colitis?
ব্যাখ্যা
Explanation: Ulcerative colitis is associated with PSC
২২.
“Thumb printing mucosa” is found in -
২৩.
Which has a high sensitivity for detecting gastrointestinal inflammation
ব্যাখ্যা
Reference: Davidson 23rd; P-818
২৪.
Most common site of Crohn’s disease
ব্যাখ্যা
Reference: Davidson 23rd; P-816
২৫.
Histological changes in ulcerative colitis
ব্যাখ্যা
Reference: Davidson 23rd; P-814
২৬.
Ulcerative colitis most commonly affects which part of gut?
২৭.
Complications of inflammatory bowel disease that are specific to Crohn’s disease-
২৮.
Which one of the following is the cardinal symptom of Ulcerative colitis?
ব্যাখ্যা
Explanation: The cardinal symptoms are rectal bleeding with passage of mucus and bloody diarrhoea.