Chronic Inflammation

Explanation :
Granulomatous inflammation is a form of chronic inflammation characterized by collections of activated macrophages, often with T lymphocytes, and sometimes associated with necrosis.
Granuloma formation is a cellular attempt to contain an offending agent that is difficult to eradicate. In this attempt there is often strong activation of T lymphocytes leading to macrophage activation, which can cause injury to normal tissues.
Epitheloid cell predominant.

Dominant cellular player in chronic inflammation is macrophage

Explanation :
Chronic inflammation is characterized by the
following:
• Infiltration with mononuclear cells, which include macrophages, lymphocytes, and plasma cells.
• Tissue destruction, induced by the persistent offending agent or by the inflammatory cells.
• Attempts at healing by connective tissue replacement of damaged tissue, accomplished by angiogenesis (proliferation of small blood vessels) and, in particular, fibrosis.

[Robbins 9th 98]

Ref. Robbins 9th p-93

Explanation :
Inflammatory arthritis -
Morning stiffness  - present 
Joint pain - Worse after rest and improved after movement 
Temperature - Raised
Joint effusion - Present
Joint crepitation  - Absent