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Acute Inflammation

মোট প্রশ্ন৩২এই পাতা৩২প্রতি পাতা১০০
প্রশ্ন দেখুনঅনুশীলন
ঘনত্ব
উত্তর
উত্তরিতবর্তমানপুনরায় দেখুনঅসম্পূর্ণ

Acute Inflammation

PrepBank · পাতা ১ / ১ · ১–৩২ / ৩২

১.
Conditions where both ESR & CRP raised
  1. ক
    ক) Sjögren’s syndrome
  2. খ
    খ) Systemic lupus erythematosus
  3. গ
    গ) Multiple myeloma
  4. ঘ
    ঘ) Polymyalgia rheumatica
ব্যাখ্যা
Reference: Davidson 23rd, Page: 72 , Box : 4.4
২.
ESR is increased disproportionately to CRP in -
  1. ক
    ক) Pregnancy
  2. খ
    খ) Multiple myeloma
  3. গ
    গ) Bacterial endocarditis
  4. ঘ
    ঘ) SLE
ব্যাখ্যা
ESR is increased disproportionately to CRP in Bacterial endocarditis
৩.
Which is not acute phase protein -
  1. ক
    Fibrinogen
  2. খ
    Heptoglobin
  3. গ
    Serum amyloid protein
  4. ঘ
    Immunoglobulin
ব্যাখ্যা
Explanation :
Acute phase proteins :
CRP,Ceruloplasmin,Cryoglobulin
Serum amyloid A protein 
Fibrinogen
Ceruloplasmin
Heptoglobin
Ferritin
Lactoferrin
৪.
The richest source of histamine is
  1. ক
    ক) Mast cell
  2. খ
    খ) Platelet
  3. গ
    গ) Basophil
  4. ঘ
    ঘ) RBC
ব্যাখ্যা
The richest source of histamine is mast cell
৫.
Acute inflammatory exudates -
  1. ক
    Has protective function
  2. খ
    Contains many eosinophils
  3. গ
    Due to chemotaxis
  4. ঘ
    Eventually calcified
ব্যাখ্যা
Explanation :
Acute inflammatory exudates :
Contains neutrophil
Rich in Fibrinogen 
Have protective function
Due to change in blood vessels
৬.
Suppurative inflammation -
  1. ক
    Is a consequences of infarction
  2. খ
    Contains polymorph
  3. গ
    Caused after Camphylobacter infection
  4. ঘ
    Is the early stage of gangrene
ব্যাখ্যা
Explanation :
Purulent inflammation is characterized by the production of pus, an exudate consisting of neutrophils, the liquefied debris of necrotic cells, and edema fluid. The most frequent cause of purulent (also called suppurative) inflammation is infection with bacteria that cause liquefactive tissue necrosis, such as staphylococci; these pathogens are referred to as pyogenic (pus-producing) bacteria.
A common example of an acute suppurative inflammation is acute appendicitis.
৭.
Source of histamine is all of the following except
  1. ক
    ক) Mast cell
  2. খ
    খ) Basophils
  3. গ
    গ) Platelets
  4. ঘ
    ঘ) Plasma
৮.
Function of leukotriene C4,D4,E4-
  1. ক
    Vasodilation
  2. খ
    Bronchospasm
  3. গ
    Chemotaxis
  4. ঘ
    Inhibition of inflammation
৯.
Mediators of fever excludes
  1. ক
    ক) IL-1
  2. খ
    খ) IL-7
  3. গ
    গ) TNF
  4. ঘ
    ঘ) Prostaglandins
১০.
Preformed chemical mediator -
  1. ক
    Prostaglandin
  2. খ
    Histamin
  3. গ
    Bradykinin
  4. ঘ
    Cytokine
ব্যাখ্যা
Explanation -
Preformed chemical mediators :
Histamine 
Serotonin
Lysosomal enzyme 
১১.
Causative agent of 'pain' in acute inflammation -
  1. ক
    C5a
  2. খ
    Bradykinin
  3. গ
    Histamin
  4. ঘ
    Leukotrines
ব্যাখ্যা
Explanation :
Causetive agents of pain in acute inflammation :
Prostaglandin 
Bradykinin
Increased K+
Decreased pH
Tissue reaction
5-HT/ serotonin
১২.
Leukocyte migration through endothelium is called-
  1. ক
    ক) Phagocytosis
  2. খ
    খ) Chemotaxis
  3. গ
    গ) Diapedesis
  4. ঘ
    ঘ) Margination
ব্যাখ্যা
Leukocyte migration through endothelium is called diapedesis
১৩.
CRP-
  1. ক
    Indirect index of acute inflammation
  2. খ
    Synthesized in blood
  3. গ
    Late indicator of acute inflammation
  4. ঘ
    Synthesis upregulated by TNF
ব্যাখ্যা
Explanation :
C-reactive protein (CRP) is a protein made by the liver.
The level of CRP increases when there's inflammation in the body.
Synthesis upregulated by TNF.
১৪.
Criteria of acute inflammation
  1. ক
    ক) Slow onset
  2. খ
    খ) Less local signs
  3. গ
    গ) Usually mild
  4. ঘ
    ঘ) Cellular infiltrate is Monocyte
১৫.
Molecules involved in ARDS
  1. ক
    ক) Neutrophils
  2. খ
    খ) Eosinophils
  3. গ
    গ) Cytokines
  4. ঘ
    ঘ) Monocytes
১৬.
Main source of TNF is
  1. ক
    ক) Macrophage
  2. খ
    খ) Platelet
  3. গ
    গ) Endothelial cell
  4. ঘ
    ঘ) Mast cell
ব্যাখ্যা
Main source of TNF is macrophage
১৭.
Mediators of pain-
  1. ক
    ক) IL-1
  2. খ
    খ) Bradykinin
  3. গ
    গ) TNF
  4. ঘ
    ঘ) Prostaglandins
ব্যাখ্যা
[Robbins 9th 90]
১৮.
Source of serotonin in acute inflammation -
  1. ক
    Mast cell
  2. খ
    Basophils
  3. গ
    Leucocytes
  4. ঘ
    Neuroendocrine cell
ব্যাখ্যা
Explanation :
Source of serotonin in acute inflammation -
Platelet 
Neuroendocrine cell
১৯.
Predominant acute inflammatory cell in first 24 hours is
  1. ক
    ক) Monocyte
  2. খ
    খ) Lymphocyte
  3. গ
    গ) Neutrophil
  4. ঘ
    ঘ) Eosinophil
ব্যাখ্যা
Predominant acute inflammatory cell in first 24 hours is neutrophil
২০.
Both ESR & CRP raised in which of the following condition?
  1. ক
    ক) Multiple myeloma
  2. খ
    খ) Acute inflammatory diseases
  3. গ
    গ) Pregnancy
  4. ঘ
    ঘ) old age
ব্যাখ্যা
Explanation: In Pregnancy, old age and multiple myeloma, isolated elevation of ESR not CRP.
২১.
Bradykinin is a mediator of
  1. ক
    ক) Tissue damage
  2. খ
    খ) Pain
  3. গ
    গ) Fever
  4. ঘ
    ঘ) Chemotaxis
২২.
Effects of complement fragment in acute inflammation -
  1. ক
    Phagocytosis
  2. খ
    Oedema
  3. গ
    Vasconstriction
  4. ঘ
    Skeletal muscle insulin resistance
ব্যাখ্যা
Explanation :
Effects of complement in acute inflammation :
Vasodilation 
Increased vascular permeability 
Phagocytosis
MAC
Chemotaxis
Leucocyte adhesion
২৩.
Oedema in acute inflammation occurs due to -
  1. ক
    Endothelial contraction
  2. খ
    Increased viscosity of blood
  3. গ
    Action of macrophage in cell
  4. ঘ
    Attempts of tissue healing
ব্যাখ্যা
Explanation 
Acute inflammatory oedema is due to -
Increased vascular permeability by endothelial cell contraction
Increased capillary hydrostatic pressure 
Breakdown of large molecules of tissue proteins
Increased fluidity of the tissue ground substance. 
২৪.
Cardinal signs of inflammation ‘calor’ means: -
  1. ক
    ক) Redness
  2. খ
    খ) Swelling
  3. গ
    গ) Heat
  4. ঘ
    ঘ) Pain
ব্যাখ্যা
[Robbins 9th 71]
২৫.
Emigration of leukocyte to the site of injury is called-
  1. ক
    ক) Phagocytosis
  2. খ
    খ) Chemotaxis
  3. গ
    গ) Diapedesis
  4. ঘ
    ঘ) Rolling
ব্যাখ্যা
Emigration of leukocyte to the site of injury is called chemotaxis
২৬.
Which metabolite of arachidonic acid vasodialator?
  1. ক
    ক) Prostacyclin
  2. খ
    খ) TXA2
  3. গ
    গ) HETE
  4. ঘ
    ঘ) Leukotriens B4
২৭.
Cause of redness in acute inflammation is-
  1. ক
    ক) Vasoconstriction
  2. খ
    খ) Stasis
  3. গ
    গ) Increased vascular permeability
  4. ঘ
    ঘ) Increase in blood flow
ব্যাখ্যা
Cause of redness in acute inflammation is increase in blood flow
২৮.
The process of coating a particle to target it for ingestion is called
  1. ক
    ক) Phagocytosis
  2. খ
    খ) Chemotaxis
  3. গ
    গ) Opsonization
  4. ঘ
    ঘ) Margination
ব্যাখ্যা
The process of coating a particle to target it for ingestion is called opsonization
২৯.
Formation of endothelial gap in venules in acute inflammation is caused by -
  1. ক
    Substance P
  2. খ
    Prostaglandin
  3. গ
    IL-8
  4. ঘ
    Chemokines
ব্যাখ্যা
Explanation :
Contraction of endothelial cells resulting in opening of interendothelial gaps is the most common mechanism of vascular leakage. It is elicited by histamine, bradykinin, leukotrienes, and other chemical mediators. 
৩০.
The following mediators increase capillary permeability except -
  1. ক
    PDGF
  2. খ
    Leucotriene
  3. গ
    Angiotensin
  4. ঘ
    Aldosterone
৩১.
Dominant leukocyte in pus is
  1. ক
    ক) Basophil
  2. খ
    খ) Neutrophil
  3. গ
    গ) Eosinophil
  4. ঘ
    ঘ) Monocyte
ব্যাখ্যা
Dominant leukocyte in pus is neutrophil
৩২.
Arachidonic acid derived mediators are called
  1. ক
    ক) Eicosanoids
  2. খ
    খ) Opsonin
  3. গ
    গ) Anaphylotoxinh
  4. ঘ
    ঘ) Complements
ব্যাখ্যা
Arachidonic acid derived mediators are called eicosanoids