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Nutritional Deficiencies

মোট প্রশ্ন৪৫এই পাতা৪৫প্রতি পাতা১০০
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Nutritional Deficiencies

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.
‘Night blindness’ is the consequence of which of the following vitamin deficiency?
  1. ক) A
  2. খ) D
  3. গ) E
  4. ঘ) K
ব্যাখ্যা
Explanation: Night blindness occurs due to Vitamin A deficiency
.
Drugs that precipitates scurvy excludes
  1. ক) Aspirin
  2. খ) Indometacin
  3. গ) Tetracycline
  4. ঘ) Carbamazepin
.
Conversion of 7-dehydrocholesterol to vitamin D occurs in which of the following site?
  1. ক) Kidney
  2. খ) Keratinocytes
  3. গ) Stratum corneum
  4. ঘ) Liver
.
Deficiency of which vitamin causes pellagra?
  1. ক) Biotin
  2. খ) Niacin
  3. গ) Thiamin
  4. ঘ) Riboflavin
ব্যাখ্যা
Explanation: Niacin Deficiency – pellagra, Thiamin Deficiency – beri-beri
.
Which deficiency leads to keshan’sdisease?
  1. ক) Vitamin B6
  2. খ) Selenium
  3. গ) Fluoride
  4. ঘ) Vitamin C
ব্যাখ্যা
Reference: Davidson 23rd , Page : 718
Explanation : keshan’s disease ( cardiomyopathy in children ) occurs due to selenium deficiency .
.
Feature of acute zinc deficiency-
  1. Eczematoid dermatitis
  2. Acrodermatitis enteropathica
  3. Dwarfism
  4. Hypogonadism
.
Dermatitis is a deficiency feature of vitamin…?
  1. ক) B6
  2. খ) B7
  3. গ) B9
  4. ঘ) B12
.
Which is not Scurvey characterized by
  1. normal synthesis of collagen
  2. perifollicular and petechial haemorrhage
  3. bruising and subperiosteal bleeding
  4. The key to diagnosis is the examination
ব্যাখ্যা
Scurvy
Vitamin C deciency affects the normal synthesis of collagen and results in a bleeding disorder characterised by perifollicular and petechial haemorrhage, bruising and subperiosteal bleeding. The key to diagnosis is the dietary history
.
‘Corkscrew hairs’ found in
  1. ক) Vitamin C deficiency
  2. খ) Vitamin A deficiency
  3. গ) Severe malnutrition
  4. ঘ) Vitamin B1 deficiency
ব্যাখ্যা
(Ref : Davidson 23rd ,p – 692 )
১০.
Pellagra occurs due to deficiency of which vitamin?
  1. ক) A
  2. খ) E
  3. গ) B1
  4. ঘ) B3
১১.
Vitamin D-
  1. Helps maintain cell membrane structure
  2. Improves immune function
  3. Affects DNA synthesis
  4. Helps in blood clotting
১২.
Which vitamin is synthesised by bacteria in the colon?
  1. Vitamin A
  2. Vitamin E
  3. Vitamin K1
  4. Vitamin K2
১৩.
BMI indicating adequate nutrition
  1. ক) >16
  2. খ) >17
  3. গ) >20
  4. ঘ) >19
১৪.
Biochemical assessment of thiamin deficiency is assessed
  1. ক) Urinary metabolite : 1 - methylnicotinamide
  2. খ) Red blood cell transketolase activity
  3. গ) Serum tocopherol : cholesterol ratio
  4. ঘ) Erythrocyte transaminase activation coefficient
ব্যাখ্যা
( Ref : Davidson 23rd ,p - 712 , box : 19.32 )
১৫.
Which one is a water-soluble vitamin?
  1. ক) A
  2. খ) B
  3. গ) D
  4. ঘ) E
ব্যাখ্যা
Explanation: Vitamins are organic substances with key roles in certain metabolic pathways, and are categorised into those that are fat-soluble (vitamins A, D, E and K) and those that are water-soluble (vitamins of the B complex group and vitamin C).
১৬.
Essential amino acid excludes
  1. ক) Phenylalanine
  2. খ) Methionine
  3. গ) Protamine
  4. ঘ) Valine
১৭.
Absorption of Vitamin B12 occurs in?
  1. 2nd part of Duodenum
  2. Jejunum
  3. Terminal ileum
  4. Large intestine
১৮.
Deficiency of following vitamin causes ataxia?
  1. B1
  2. B2
  3. B3
  4. B6
১৯.
A 58-year-old man with a history of chronic alcohol use presents with confusion, ataxia, and nystagmus. His condition rapidly improves after administration of thiamine. What is the most likely diagnosis?
  1. Wernicke’s encephalopathy
  2. Korsakoff’s syndrome
  3. Alcohol withdrawal
  4. Hepatic encephalopathy
ব্যাখ্যা
Stem Breakdown:

Confusion, ataxia, and nystagmus: This classic triad of symptoms is highly suggestive of Wernicke's encephalopathy, a neurological disorder associated with thiamine (vitamin B1) deficiency.
Chronic alcohol use: Chronic alcoholism is the most common cause of thiamine deficiency, leading to Wernicke's encephalopathy.
Rapid improvement with thiamine: This confirms that the symptoms were due to thiamine deficiency, which is rapidly reversible with appropriate supplementation.
Option Analysis:

A) Wernicke’s encephalopathy: This is the correct diagnosis. Davidson and Harrison both highlight that Wernicke’s encephalopathy is caused by thiamine deficiency, commonly seen in chronic alcoholics. The classic symptoms include confusion, ataxia, and ophthalmoplegia (nystagmus or other eye movement abnormalities). Rapid improvement with thiamine supports this diagnosis.
B) Korsakoff’s syndrome: Korsakoff's syndrome is a chronic sequela of untreated Wernicke’s encephalopathy, characterised by irreversible memory loss and confabulation. It does not cause rapid neurological improvement with thiamine administration.
C) Alcohol withdrawal: Alcohol withdrawal causes symptoms such as tremors, agitation, and hallucinations, but it does not typically present with the triad of confusion, ataxia, and nystagmus.
D) Hepatic encephalopathy: Hepatic encephalopathy occurs in patients with liver failure and is due to elevated ammonia levels. It presents with altered mental status but not with the other signs of Wernicke's (ataxia, nystagmus).
২০.
Cardiomyopathy results from deficiency of
  1. ক) Zinc
  2. খ) Iron
  3. গ) Cobalt
  4. ঘ) Selenium
২১.
Under Nutrition is indicated where BMI
  1. <18.5
  2. 18.5-20
  3. >20
  4. >18.5
ব্যাখ্যা
২২.
Followings are Essential amino acid, excludes?
  1. ক) Tryptophan
  2. খ) Histidine
  3. গ) Serine
  4. ঘ) Methionine
২৩.
Which of the following is an essential amino acid?
  1. ক) Methionine
  2. খ) Serine
  3. গ) Glutamate
  4. ঘ) Choline
২৪.
Parameter that is monitored weekly in patients receiving parenteral nutrition in hospital?
  1. Electrolytes
  2. Liver function test
  3. Cholesterol
  4. C-reactive protein
২৫.
Which one is a rich source of vitamin C?
  1. ক) Citrus fruit
  2. খ) Fresh fruit
  3. গ) fresh and frozen vegetables
  4. ঘ) Liver
ব্যাখ্যা
Davidson 23rd, Box-19.28
২৬.
Example of fat soluble vitamin-
  1. Thiamin
  2. Pyridoxine
  3. Tocopherol
  4. Cobalamin
২৭.
Wernicke’s encephalopathy is caused by which of the following vitamin deficiency?
  1. ক) Thiamin
  2. খ) Riboflavin
  3. গ) Niacin
  4. ঘ) Pyridoxine
ব্যাখ্যা
Explanation: Dry (or neurological) beri-beri manifests with chronic peripheral neuropathy and with wrist and/or foot drop, and may cause Korsakoff’s psychosis and Wernicke’s encephalopathy
২৮.
Defficiency of folate level is best assessed by which of the following invstigation?
  1. ক) RBC folate level
  2. খ) S.Ferritin
  3. গ) Plasma folate level
  4. ঘ) Bone marrow folote level
ব্যাখ্যা
Explanation: Red cell folate levels are a more accurate indicator of folate stores and tissue folate deficiency.
২৯.
Coffee is a rich source of
  1. ক) Sodium
  2. খ) Potassium
  3. গ) Calcium
  4. ঘ) Magnesium
৩০.
A 24 year old lady came to your chamber with complaints of Extreme cachexia with history of diet control, heavy exercise, induced vomiting and amenorrhea .Diagnosis will be
  1. avoidant restrictive food intake disorder
  2. anorexia nervosa
  3. binge eating disorder
  4. bulimia nervosa
৩১.
Which nutrient deficiency can be seen in case of prolonged parenteral nutrition?
  1. Zinc
  2. Selenium
  3. Chromium
  4. Copper
৩২.
In which is site carotenemia is not seen
  1. Face
  2. Sole
  3. Conjunctiva
  4. Palm
ব্যাখ্যা
Hypercarotenaemia occurs due to excessive ingestion of carotene-containing vegetables or in situations of impaired metabolism such as hypothyroidism or anorexia nervosa.

A yellowish discoloration is seen on the face, palms and soles but not the sclera or conjunctiva, and this distinguishes it from jaundice 


Macledo 14th/P-26
৩৩.
Iodine is rich in
  1. ক) Liver
  2. খ) Shellfish
  3. গ) Sea food
  4. ঘ) Edible seaweeds
ব্যাখ্যা
Reference: Davidson 23rd , Page : 717 , Box : 19.34
৩৪.
Which vitamin deficiency is seen in carcinoid syndrome?
  1. ক) Thiamine deficiency
  2. খ) Riboflavin deficiency
  3. গ) Niacin deficiency
  4. ঘ) Pyridoxine deficiency
ব্যাখ্যা
Reference: Davidson 23rd , Page : 1233
Explanation : Niacin deficiency ( Vitamin B3 ) - pellagra can also seem in carcinoid syndrome.
৩৫.
Biochemical assessment of vitamin B2 deficiency is assessed by
  1. ক) Erythrocyte transaminase activation coefficient
  2. খ) Serum tocopherol: cholesterol ratio
  3. গ) Red blood cell glutathione reductase activity
  4. ঘ) Red blood cell transketolase activity
ব্যাখ্যা
Reference: Davidson 23rd , Page : 712 , Box : 29.32
৩৬.
The World Health Organization (WHO) recommends a minimum intake of --- μg/day iodine
  1. 150
  2. 250
  3. 350
  4. 450
৩৭.
Water soluble vitamin is-
  1. Retinol
  2. Tocopherol
  3. Phylloquinone
  4. Cobalamin
৩৮.
Urinary metabolites are used for biochemical assessment of vitamin
  1. ক) B1
  2. খ) B2
  3. গ) B3
  4. ঘ) B6
৩৯.
Milk is a rich source of vitamin
  1. ক) B1
  2. খ) B2
  3. গ) B3
  4. ঘ) B6
৪০.
Which of the following is not a function of Vitamin E?
  1. It prevents oxidation of polyunsaturated fatty acids in cell membranes by free radicals.
  2. It helps maintain cell membrane structure.
  3. It affects RNA synthesis and cell signalling
  4. It is involved in the anti inflammatory and immune systems.
৪১.
Deficiency of which vitamin may causes high output cardiac failure?
  1. Thaiamine
  2. Riboflavin
  3. Niacin
  4. Pyridoxine
ব্যাখ্যা
High-output failure
Sometimes cardiac failure can occur in patients without heart disease
due to a large arteriovenous shunt, or where there is an excessively high
cardiac output due to beri-beri, severe anaemia or thyrotoxicosis.
৪২.
Which of the following is responsible for pathological fracture?
  1. Osteomalacia
  2. Osteoporosis
  3. Rheumatoid arthritis
  4. Potts disease
৪৩.
Which vitamin is synthesised by bacteria in the colon?
  1. Vitamin K1
  2. Vitamin K2
  3. Vitamin D
  4. Vitamin E
৪৪.
Muscle function and global nutritional status is measured by
  1. ক) Waist : hip ratio
  2. খ) Bio electrical impedance
  3. গ) Hand grip strength
  4. ঘ) Triceps skin fold thickness
ব্যাখ্যা
( Ref : Davidson 23rd ,p –693 )
৪৫.
Acrodermatitis enteropathica is a consequence of which nutrient malabsorption?
  1. Vitamin A
  2. Vitamin C
  3. Zinc
  4. Magnesium