Reference: Davidson 23rd , Page : 718 Explanation : keshan’s disease ( cardiomyopathy in children ) occurs due to selenium deficiency .
৬.
Feature of acute zinc deficiency-
ক
Eczematoid dermatitis
খ
Acrodermatitis enteropathica
গ
Dwarfism
ঘ
Hypogonadism
৭.
Dermatitis is a deficiency feature of vitamin…?
ক
ক) B6
খ
খ) B7
গ
গ) B9
ঘ
ঘ) B12
৮.
Which is not Scurvey characterized by
ক
normal synthesis of collagen
খ
perifollicular and petechial haemorrhage
গ
bruising and subperiosteal bleeding
ঘ
The key to diagnosis is the examination
ব্যাখ্যা
Scurvy Vitamin C deciency affects the normal synthesis of collagen and results in a bleeding disorder characterised by perifollicular and petechial haemorrhage, bruising and subperiosteal bleeding. The key to diagnosis is the dietary history
৯.
‘Corkscrew hairs’ found in
ক
ক) Vitamin C deficiency
খ
খ) Vitamin A deficiency
গ
গ) Severe malnutrition
ঘ
ঘ) Vitamin B1 deficiency
ব্যাখ্যা
(Ref : Davidson 23rd ,p – 692 )
১০.
Pellagra occurs due to deficiency of which vitamin?
ক
ক) A
খ
খ) E
গ
গ) B1
ঘ
ঘ) B3
১১.
Vitamin D-
ক
Helps maintain cell membrane structure
খ
Improves immune function
গ
Affects DNA synthesis
ঘ
Helps in blood clotting
১২.
Which vitamin is synthesised by bacteria in the colon?
ক
Vitamin A
খ
Vitamin E
গ
Vitamin K1
ঘ
Vitamin K2
১৩.
BMI indicating adequate nutrition
ক
ক) >16
খ
খ) >17
গ
গ) >20
ঘ
ঘ) >19
১৪.
Biochemical assessment of thiamin deficiency is assessed
Explanation: Vitamins are organic substances with key roles in certain metabolic pathways, and are categorised into those that are fat-soluble (vitamins A, D, E and K) and those that are water-soluble (vitamins of the B complex group and vitamin C).
১৬.
Essential amino acid excludes
ক
ক) Phenylalanine
খ
খ) Methionine
গ
গ) Protamine
ঘ
ঘ) Valine
১৭.
Absorption of Vitamin B12 occurs in?
ক
2nd part of Duodenum
খ
Jejunum
গ
Terminal ileum
ঘ
Large intestine
১৮.
Deficiency of following vitamin causes ataxia?
ক
B1
খ
B2
গ
B3
ঘ
B6
১৯.
A 58-year-old man with a history of chronic alcohol use presents with confusion, ataxia, and nystagmus. His condition rapidly improves after administration of thiamine. What is the most likely diagnosis?
ক
Wernicke’s encephalopathy
খ
Korsakoff’s syndrome
গ
Alcohol withdrawal
ঘ
Hepatic encephalopathy
ব্যাখ্যা
Stem Breakdown:
Confusion, ataxia, and nystagmus: This classic triad of symptoms is highly suggestive of Wernicke's encephalopathy, a neurological disorder associated with thiamine (vitamin B1) deficiency. Chronic alcohol use: Chronic alcoholism is the most common cause of thiamine deficiency, leading to Wernicke's encephalopathy. Rapid improvement with thiamine: This confirms that the symptoms were due to thiamine deficiency, which is rapidly reversible with appropriate supplementation. Option Analysis:
A) Wernicke’s encephalopathy: This is the correct diagnosis. Davidson and Harrison both highlight that Wernicke’s encephalopathy is caused by thiamine deficiency, commonly seen in chronic alcoholics. The classic symptoms include confusion, ataxia, and ophthalmoplegia (nystagmus or other eye movement abnormalities). Rapid improvement with thiamine supports this diagnosis. B) Korsakoff’s syndrome: Korsakoff's syndrome is a chronic sequela of untreated Wernicke’s encephalopathy, characterised by irreversible memory loss and confabulation. It does not cause rapid neurological improvement with thiamine administration. C) Alcohol withdrawal: Alcohol withdrawal causes symptoms such as tremors, agitation, and hallucinations, but it does not typically present with the triad of confusion, ataxia, and nystagmus. D) Hepatic encephalopathy: Hepatic encephalopathy occurs in patients with liver failure and is due to elevated ammonia levels. It presents with altered mental status but not with the other signs of Wernicke's (ataxia, nystagmus).
২০.
Cardiomyopathy results from deficiency of
ক
ক) Zinc
খ
খ) Iron
গ
গ) Cobalt
ঘ
ঘ) Selenium
২১.
Under Nutrition is indicated where BMI
ক
<18.5
খ
18.5-20
গ
>20
ঘ
>18.5
ব্যাখ্যা
২২.
Followings are Essential amino acid, excludes?
ক
ক) Tryptophan
খ
খ) Histidine
গ
গ) Serine
ঘ
ঘ) Methionine
২৩.
Which of the following is an essential amino acid?
ক
ক) Methionine
খ
খ) Serine
গ
গ) Glutamate
ঘ
ঘ) Choline
২৪.
Parameter that is monitored weekly in patients receiving parenteral nutrition in hospital?
ক
Electrolytes
খ
Liver function test
গ
Cholesterol
ঘ
C-reactive protein
২৫.
Which one is a rich source of vitamin C?
ক
ক) Citrus fruit
খ
খ) Fresh fruit
গ
গ) fresh and frozen vegetables
ঘ
ঘ) Liver
ব্যাখ্যা
Davidson 23rd, Box-19.28
২৬.
Example of fat soluble vitamin-
ক
Thiamin
খ
Pyridoxine
গ
Tocopherol
ঘ
Cobalamin
২৭.
Wernicke’s encephalopathy is caused by which of the following vitamin deficiency?
ক
ক) Thiamin
খ
খ) Riboflavin
গ
গ) Niacin
ঘ
ঘ) Pyridoxine
ব্যাখ্যা
Explanation: Dry (or neurological) beri-beri manifests with chronic peripheral neuropathy and with wrist and/or foot drop, and may cause Korsakoff’s psychosis and Wernicke’s encephalopathy
২৮.
Defficiency of folate level is best assessed by which of the following invstigation?
ক
ক) RBC folate level
খ
খ) S.Ferritin
গ
গ) Plasma folate level
ঘ
ঘ) Bone marrow folote level
ব্যাখ্যা
Explanation: Red cell folate levels are a more accurate indicator of folate stores and tissue folate deficiency.
২৯.
Coffee is a rich source of
ক
ক) Sodium
খ
খ) Potassium
গ
গ) Calcium
ঘ
ঘ) Magnesium
৩০.
A 24 year old lady came to your chamber with complaints of Extreme cachexia with history of diet control, heavy exercise, induced vomiting and amenorrhea .Diagnosis will be
ক
avoidant restrictive food intake disorder
খ
anorexia nervosa
গ
binge eating disorder
ঘ
bulimia nervosa
৩১.
Which nutrient deficiency can be seen in case of prolonged parenteral nutrition?
ক
Zinc
খ
Selenium
গ
Chromium
ঘ
Copper
৩২.
In which is site carotenemia is not seen
ক
Face
খ
Sole
গ
Conjunctiva
ঘ
Palm
ব্যাখ্যা
Hypercarotenaemia occurs due to excessive ingestion of carotene-containing vegetables or in situations of impaired metabolism such as hypothyroidism or anorexia nervosa.
A yellowish discoloration is seen on the face, palms and soles but not the sclera or conjunctiva, and this distinguishes it from jaundice