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স্পেশাল বিসিএস (স্বাস্থ্য) - লং কোর্স

পরীক্ষাস্পেশাল বিসিএস (স্বাস্থ্য) - লং কোর্সতারিখতারিখ অনির্ধারিতসময়20 minutes
মোট প্রশ্ন৪০
সিলেবাস
টপিক: Medicine – 7 Nephrology, Acid Base & Electrolyte disorders
ঘনত্ব
উত্তর
উত্তরিতবর্তমানপুনরায় দেখুনঅসম্পূর্ণ

স্পেশাল বিসিএস (স্বাস্থ্য) - লং কোর্স

স্পেশাল বিসিএস (স্বাস্থ্য) - লং কোর্স · তারিখ অনির্ধারিত · ৪০ প্রশ্ন

.
eGFR is not valid in assessing
  1. Patients undergoing Renal Transplantation
  2. Chronic kidney injury
  3. Acute kidney injury
  4. ADPKD
.
1st symptom usually occur at CKD when GFR below
  1. 10
  2. 20
  3. 25
  4. 30
.
Length of each adult kidney is
  1. 10 -13cm
  2. 8-12mm
  3. 10-13 mm
  4. 8-12cm
ব্যাখ্যা
Each kidney is approximately 10–13 cm in length in healthy adults;they are located retroperitoneally on either side of the aorta and inferior vena cava between the 12th thoracic and 3rd lumbar vertebrae (Fig. 18.1A). The right kidney is usually a few centimetres lower because the liver lies above it. Both kidneys rise and descend several centimetres with respiration.
.
Kidney produces following
  1. Erythropoietin
  2. Rennin
  3. D2
  4. Kinins
.
Macula densa is stimulated by
  1. Na
  2. K
  3. Mg
  4. Ca
.
Renal blood flow is ----- %of CO
  1. 13
  2. 15
  3. 20
  4. 25
.
Constriction of afferent arteriole causes no change in
  1. Filtration fraction
  2. RPF
  3. GFR
  4. Creatinine
.
Angiotension II does not work on
  1. Adrenal medulla
  2. Adrenal cortex
  3. Brain
  4. Vessel
.
Passive reabsorption in tubules occur for following
  1. Urea
  2. K
  3. Na
  4. Amino acid
১০.
Which is not true for sodium transport
  1. 67% in PCT
  2. <1% in excretion
  3. 10% in Thin descending limb
  4. 25% in thick ascending limb
১১.
Medullary hyper osmolarity is maintained by
  1. active transport of ions
  2. passive diffusion of urea
  3. low medullary blood flow
  4. Diffusion of water
১২.
A 60 years old active smoker presented with disorientation. His Na level is 115 mmol/L. What is the cause?
  1. CCF
  2. NS
  3. SIADH
  4. Cushing syndrome
১৩.
Hyperkalemia is caused by
  1. Barter syndrome
  2. Liddle syndrome
  3. Gettleman syndrome
  4. congenital adrenal Hyperplasia
১৪.
Which of the following is not causing Hypokalaemia with hypertension
  1. Cushing's syndrome
  2. primary hyperaldosteronism
  3. Liddle's syndrome
  4. 11-beta hydroxylase
১৫.
Acid base balance is maintained by -----no of equations
  1. 1
  2. 2
  3. 3
  4. 4
ব্যাখ্যা
2 equations
1.Hendersson  Hasslebach equation
2.Anion  Gap
১৬.
Metabolic acidosis is associated with all of the followings except:
  1. Methanol poisoning
  2. RTA
  3. Vomiting
  4. Lactic acidosis
১৭.
Which is not a cardinal feature of RTA type 1
  1. Normal anion gap metabolic acidosis
  2. Hyperkalemia
  3. Hypercalciuria and nephrocalcinosis
  4. Osteomalacia
ব্যাখ্যা
Type I RTA is characterized by:

•Impaired hydrogen ion secretion in Distal  tubule
•Hypokalemia
•Hypocitraturia
•Hypercalciuria
•Nephrocalcinosis
•Renal Stones
১৮.
Cause of Chloride responsive Metabolic alkalosis
  1. Conn’s syndrome
  2. Cushing’s syndrome
  3. Chronic hypokalemia
  4. Ingestion of Alkaline Drugs
ব্যাখ্যা
Saline/ Chloride responsive:  Associated with hypovolemia and  responds to N/S infusion

•Ingestion of Alkaline Drugs
•GIT Cause
•Diuretic administration
১৯.
Dipstick positive occurs in
  1. Myoglobinuria
  2. Haemoglobinuria
  3. Hematuria
  4. All
ব্যাখ্যা
Dipstick positive
•Hematuria
•Haemoglobinuria
•Myoglobinuria
২০.
Gross hematuria occurs in
  1. IgA nephropathy
  2. Alport syndrome
  3. Tumor
  4. All
ব্যাখ্যা
GROSS  HEMATURIA
•Trauma
•Tumor
•IgA nephropathy
•Alport syndrome
২১.
Low complementemia doesn't found in
  1. PIGN
  2. AGN
  3. SBE
  4. SLE
২২.
Most Common cause of CKd in Bangladesh?
  1. DM
  2. GN
  3. Unknown
  4. Genetic
২৩.
In adynamic bone disease following are increased except
  1. Ca
  2. PO4
  3. K
  4. PTH
২৪.
NS is associated with daily loss of------------protein
  1. 2.5 gm
  2. 3.5gm
  3. 1.5gm
  4. 4 gm
ব্যাখ্যা
1.
Massive proteinuria, with the daily loss of 3.5 gm or more of protein (less in children)
2.
Hypoalbuminemia, with plasma albumin levels  less than 3 gm/dL
3.
Generalized edema
4.
Hyperlipidemia and lipiduria
২৫.
Proximal RTA is characterized  by
  1. Failure to thrive
  2. Hyperphosphaturia
  3. Hypokalemia
  4. All
ব্যাখ্যা
Type II (proximal) RTA is characterized  by
•Hypokalemia
•Hyperphosphaturia
•Aminoaciduria
•Glycosuria
•Rickets and osteomalacia
•Failure to thrive
২৬.
Type A lactic acidosis is caused by
  1. Cyanide
  2. Diabetes mellitus
  3. Severe sepsis
  4. Metformin
ব্যাখ্যা
Type B: Impaired Lactic acid  metabolism
•Severe sepsis
•Hepatic & Renal failure
•Drugs- Metformin, Ethanol
•Diabetes mellitus
Type A: Increased production, due to:
Hypotension – Shock, Cardiac failure
Tissue hypoxia:
Mitochondrial  dysfunction (CO, Cyanide) Severe anemia
২৭.
The minor unmeasured cations are
  1. gamma globulins
  2. magnesium
  3. Sodium
  4. calcium
ব্যাখ্যা
The major unmeasured cations are calcium,  magnesium, gamma globulins.
২৮.
Renal Acid base balance is maintained by
  1. Reabsorption of filtered HCO3
  2. Secretion of H+
  3. Production of new HCO3
  4. All
২৯.
ECG changes in Hypokalemia 
  1. Peaked T waves
  2. Prolonged QRS duration with bizarre QRS morphology
  3. Development of a sine wave appearance
  4. Apparent long QT interval
ব্যাখ্যা
ECG changes in Hypokalemia 
T wave flattening and  inversion
·Prominent U wave
·Increased amplitude and  width of the P wave
·Prolongation of the PR  interval
·ST depression
·Apparent long QT interval
(= long QU interval)

·Supraventricular  tachyarrhythmias: AF, atrial  flutter, atrial tachycardia
·life-threatening ventricular  arrhythmias, e.g. VT, VF and  Torsades de Pointes
৩০.
The earliest sign of hyperkalaemia is associated with
  1. P
  2. Q
  3. S
  4. T
৩১.
Drug causes Hyperkalemia
  1. Eplerenone
  2. Angiotensin-converting enzyme (ACE) inhibitors
  3. β-blockers
  4. All
ব্যাখ্যা
Hyperkalemia
Drug causes
β-blockers
·Angiotensin-converting enzyme (ACE) inhibitors
·Angiotensin-receptor blockers (ARBs)
·Spironolactone
·Eplerenone
·Calcineurin inhibitors: Cyclosporin, Tacrolimus
৩২.
Main mediator of water balance
  1. ADH
  2. Na
  3. ACTH
  4. Aldosterone
৩৩.
In decreased thirst all are decreased except
  1. Osmolarity
  2. Blood volume
  3. AII
  4. Dryness of mouth
৩৪.
In ECF following level are lower except
  1. Amino acids
  2. fats
  3. pH
  4. Proteins
৩৫.
Calculate TBW in a 60 kg adult man
  1. 42 L
  2. 45 L
  3. 36 L
  4. 48L
ব্যাখ্যা
Total body water (TBW) is approximately 60% of body  weight. (42 L in a 70 Kg man)
৩৬.
Agents not causing contraction of mesangial cells
  1. Angiotensin II
  2. vasopressin
  3. PGE2
  4. Norepinephrine
৩৭.
Large proteins are blocked by
  1. Podocytes
  2. Fenestrations of capillary endothelium
  3. Glomerular Basement Membrane
  4. Slit diaphragms
৩৮.
Angiotensin II doesn’t work by
  1. By Decreasing The Sensitivity Of The Baroreflex
  2. By Decreasing The Secretion Of Vasopressin (ADH) And ACTH
  3. Rise In Systolic And Diastolic Blood Pressure.
  4. Constriction Of Efferent Arteriole
৩৯.
Conditions decrease renin secretion
  1. Na Depletion
  2. Diuretics
  3. Cardiac failure
  4. increased osmolarity
৪০.
Which is a Na Channel blocker
  1. Spironolactone
  2. Mannitol
  3. Amiloride
  4. Loop Diuretics