২০১.
Late feature of cholestatic jaundice is?
PrepBank · বিষয়ভিত্তিক প্রশ্ন
Gastrointestinal & Hepatobiliary
Gastrointestinal & Hepatobiliary
PrepBank · পাতা ৩ / ৩ · ২০১–২১৫ / ২১৫
২০২.
A 34-year-old woman presents with abdominal pain and jaundice. Her liver enzymes are elevated, and her serum ceruloplasmin levels are low. Which of the following is the most likely diagnosis?
ব্যাখ্যা
Stem Breakdown:
Abdominal pain and jaundice: These symptoms indicate liver dysfunction, which can be seen in several liver conditions.
Elevated liver enzymes: suggests hepatocellular injury, as seen in liver diseases that cause inflammation or damage to hepatocytes.
Low serum ceruloplasmin: This is the key finding pointing towards Wilson’s disease, a disorder of copper metabolism where ceruloplasmin (the copper-carrying protein in blood) is deficient.
Option Analysis:
A) Wilson’s disease: This is the correct diagnosis. Davidson explains that Wilson’s disease is caused by a genetic defect in copper excretion, leading to copper accumulation in various tissues, including the liver and brain. Harrison adds that low ceruloplasmin levels and liver involvement are key diagnostic features, often presenting in young adults with hepatic or neuropsychiatric symptoms.
B) Hemochromatosis: This is a disorder of iron overload, not copper. It leads to increased serum iron and ferritin, not ceruloplasmin. While hemochromatosis can cause liver disease, it does not present with low ceruloplasmin levels.
C) Autoimmune hepatitis: Autoimmune hepatitis presents with elevated liver enzymes and positive autoantibodies (e.g., ANA, SMA), but ceruloplasmin levels are not affected.
D) Primary biliary cholangitis (PBC): PBC is an autoimmune condition affecting the bile ducts, leading to cholestasis and jaundice. It is associated with elevated alkaline phosphatase and antimitochondrial antibodies (AMA), but not low ceruloplasmin.
Abdominal pain and jaundice: These symptoms indicate liver dysfunction, which can be seen in several liver conditions.
Elevated liver enzymes: suggests hepatocellular injury, as seen in liver diseases that cause inflammation or damage to hepatocytes.
Low serum ceruloplasmin: This is the key finding pointing towards Wilson’s disease, a disorder of copper metabolism where ceruloplasmin (the copper-carrying protein in blood) is deficient.
Option Analysis:
A) Wilson’s disease: This is the correct diagnosis. Davidson explains that Wilson’s disease is caused by a genetic defect in copper excretion, leading to copper accumulation in various tissues, including the liver and brain. Harrison adds that low ceruloplasmin levels and liver involvement are key diagnostic features, often presenting in young adults with hepatic or neuropsychiatric symptoms.
B) Hemochromatosis: This is a disorder of iron overload, not copper. It leads to increased serum iron and ferritin, not ceruloplasmin. While hemochromatosis can cause liver disease, it does not present with low ceruloplasmin levels.
C) Autoimmune hepatitis: Autoimmune hepatitis presents with elevated liver enzymes and positive autoantibodies (e.g., ANA, SMA), but ceruloplasmin levels are not affected.
D) Primary biliary cholangitis (PBC): PBC is an autoimmune condition affecting the bile ducts, leading to cholestasis and jaundice. It is associated with elevated alkaline phosphatase and antimitochondrial antibodies (AMA), but not low ceruloplasmin.
২০৩.
Poor wound healing is associated with malabsorption of following except
ব্যাখ্যা
Reference: Davidson 23rd; P-784
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
২০৪.
Initial test for chronic hepatitis B
ব্যাখ্যা
Reference: Davidson 23rd; P-854
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
২০৫.
Multiple doses of activated charcoal can eliminate all of the following except
ব্যাখ্যা
Reference: Davidson 23rd; P-136
২০৬.
After immunization of Hepatitis B virus infection which of the serological test become positive?
ব্যাখ্যা
Reference: Davidson 23rd, Box-22.38
২০৭.
Which one is the gold standard investigation for pancreatic function assesment?
ব্যাখ্যা
Reference: Davidson 23rd, Box-21.84
২০৮.
Which of the following is responsible for transudative ascites?
২০৯.
Abdominal pain is the most common symptom of liver abscess which usually in which of the following areas of the liver?
ব্যাখ্যা
Explanation: Abdominal pain is the most common symptom and is usually in the right upper quadrant, sometimes with radiation to the right shoulder. The pain may be pleuritic in nature.
২১০.
Complicatiion that can arise from both acute and chronic pancreatitis
ব্যাখ্যা
Reference: Davidson 23rd; P-841
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
২১১.
Osmotic laxative
ব্যাখ্যা
Reference: Davidson 23rd; P-834
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
২১২.
Which one of the following is the cardinal symptom of Ulcerative colitis?
ব্যাখ্যা
Explanation: The cardinal symptoms are rectal bleeding with passage of mucus and bloody diarrhoea.
২১৩.
Which one is a sign of decompression in hepatic cirrhosis?
২১৪.
Silvery stool is found in
২১৫.
Which can confirm acute pancreatitis?
ব্যাখ্যা
Reference: Davidson 23rd; P-839
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]
সলভ ক্লাসের জন্য আলোচনা পোস্ট দেখুন - [আলোচনা পোস্টের লিঙ্ক]