বিষয়সমূহ

PrepBank · বিষয়ভিত্তিক প্রশ্ন

স্পেশাল বিসিএস (স্বাস্থ্য)

মোট প্রশ্ন৪,২৮৫এই পাতা১০০প্রতি পাতা১০০
ঘনত্ব
উত্তর
উত্তরিতবর্তমানপুনরায় দেখুনঅসম্পূর্ণ

স্পেশাল বিসিএস (স্বাস্থ্য)

PrepBank · পাতা ১৪ / ৪৩ · ১,৩০১১,৪০০ / ৪,২৮৫

১,৩০১.
Cavernous sinus not consist of ________CN
  1. 3rd
  2. 4th
  3. 5th
  4. 6th
ব্যাখ্যা
Extension of pituitary tumor into avernous sinus with subsequent compression of the 3rd, 4th or 6th  cranial nerve may cause diplopia and strabismus, but in anterior pituitary  tumours this is an unusual presentation.

Davidson 24th-695
১,৩০২.
If a medical officer fails to appear in court after being summoned under CrPC Section 160, it can result in:
  1. Dismissal from job
  2. No consequence if busy
  3. Legal penalty for contempt of court
  4. Reassignment of the case
ব্যাখ্যা
Under the CrPC, failure to comply with a lawful summons can result in contempt proceedings. Reddy warns that absence without valid cause can damage the case and lead to legal consequences
Summary procedure for punishment for non-attendance by a witness in obedience to summons
1[485A.(1) If any witness being summoned to appear before a Criminal Court is legally bound to appear at a certain place and time in obedience to the summons and without just excuse neglects or refuses to attend at that place or time or departs from the place where he has to attend before the time at which it is lawful for him to depart, and the Court before which the witness is to appear is satisfied that it is expedient in the interests of justice that such a witness should be tried summarily, the Court, may take cognizance of the offence and after given the offender an opportunity of showing cause why he should not be punished under this section, sentence him to fine not exceeding Taka two hundred and fifty. 
 
 
(2) In every such case the Court shall follow, as nearly as may be practicable, the procedure prescribed for summary trials.]
১,৩০৩.
In Down’s syndrome there is high incidence of
  1. ক) Lymphoma
  2. খ) Leukemia
  3. গ) Lung cancer
  4. ঘ) Prostate cancer
১,৩০৪.
Heart rate is accelerated by
  1. ক) Exercise
  2. খ) Fear
  3. গ) increased baroreceptor activity
  4. ঘ) increased intracranial pressure
ব্যাখ্যা
Reference-Ganong physiology/26th/P-580/T-32-3
১,৩০৫.
Angiogenesis is promoted by
  1. ক) Hypoxia inhibitory factor
  2. খ) Endostatin
  3. গ) Thrombospondin
  4. ঘ) PDGF
ব্যাখ্যা
Angiogenesis is promoted by PDGF
১,৩০৬.
“supplies oxygenated blood to hepatocyte”-
  1. ক) Classic hepatic lobule
  2. খ) Portal lobule
  3. গ) Hepatic acinus
  4. ঘ) Cystic lobule
১,৩০৭.
Retrobulbar neuritis is a major adverse reaction observed in therapy with
  1. ক) Isoniazid
  2. খ) Ethambutol
  3. গ) Pyrazinamide
  4. ঘ) Streptomycin
ব্যাখ্যা
Reference: Davidson 23rd; P-593
১,৩০৮.
Diagnostic feature of Beta thalassaemia major -
  1. Microcytic hypochromic anaemia
  2. Punctate basophilia
  3. Raised Hb A2 fraction
  4. Raised levels of Hb F
১,৩০৯.
Which is not a histological features of Ulcerative colitis?
  1. ক) crypt distortion
  2. খ) cryptitis
  3. গ) crypt abscesses
  4. ঘ) numerous goblet cells
ব্যাখ্যা
Explanation: histological features of Ulcerative colitis are: Inflammation limited to mucosa, crypt distortion, cryptitis, crypt abscesses, loss of goblet cells,
১,৩১০.
PCV increases in
  1. Anemia
  2. Cirrhosis of liver
  3. Pregnancy
  4. Dengue shock syndrome
ব্যাখ্যা

Explanations:
PCV decreases in:
• Anemia
• Cirrhosis of liver
• Pregnancy
• Hemorrhage due to ectopic pregnancy

১,৩১১.
What is the excitatory cell of cerebellum?
  1. ক) Granule cells
  2. খ) Basket cells
  3. গ) Golgi cells
  4. ঘ) Purkinje cells
ব্যাখ্যা
Explanation : Climbing & Mossy fibres,Granule cells are excitatory neuron in cerebellum.Stellate,basket,golgi & purkinje cells are inhibitory neuron of cerebellum.
Ref : Sembulingam 6th edition (Table-150.2)
১,৩১২.
Which may be detected in glomerulonephritis secondary to systemic vasculitis?
  1. ক) ANA
  2. খ) Anti dsDNA
  3. গ) ANCAs
  4. ঘ) Antibodies to GBM
ব্যাখ্যা
Reference: Davidson 23rd; P-389
১,৩১৩.
Whinch one is the specific benzodiazepine antagonist?
  1. ক) Naloxone
  2. খ) Acetylcysteine
  3. গ) Atropine
  4. ঘ) Flumazenil
ব্যাখ্যা
Explanation: The specific benzodiazepine antagonist flumazenil (0.5 mg IV, repeated if needed) increases conscious level in patients with benzodiazepine overdose
১,৩১৪.
Delayed relaxation of grip indicates
  1. ক) Myotonic dystrophy
  2. খ) Hypothyroidism
  3. গ) Depression
  4. ঘ) Anxiety
১,৩১৫.
Cause of heart failure due to increased metabolic demand-
  1. Myocardial infarction
  2. Diabetes mellitus
  3. Patent ductus arteriosus
  4. Paget’s disease
ব্যাখ্যা
Macleod's Clinical Examination, Page-46
১,৩১৬.
URTI are mostly
  1. ক) Bacterial
  2. খ) Viral
  3. গ) Fungal
  4. ঘ) Parasitic
ব্যাখ্যা
Reference: Davidson 23rd; P-581
১,৩১৭.
Features of heat exhaustion-
  1. Muscle spasms related to sodium loss
  2. Normal mental status
  3. Neurological impairment with core body temperature ≥ 40°C
  4. Sweating may be absent
১,৩১৮.
Biochemical assessment of thiamin deficiency is assessed
  1. ক) Urinary metabolite : 1 - methylnicotinamide
  2. খ) Red blood cell transketolase activity
  3. গ) Serum tocopherol : cholesterol ratio
  4. ঘ) Erythrocyte transaminase activation coefficient
ব্যাখ্যা
( Ref : Davidson 23rd ,p - 712 , box : 19.32 )
১,৩১৯.
Which is not a feature of Tabes Paresis
  1. Lateral Colum Lesion
  2. Charcot pain
  3. Shooting pain
  4. ARP
ব্যাখ্যা
Tabes Dorsalis morphology:
DORSALIS
1. Dorsal column degeneration
2. Orthopedic pain (Charcot joints)
3. Reflexes decreased (deep tendon)
4. Shooting pain
5. Argyll-Robertson pupils
6. Locomotor ataxia
7. Impaired proprioception
8. Syphilis
১,৩২০.
Dog is the definitive host in following parasite:
  1. ক) E. histolytica
  2. খ) Acanthamoeba
  3. গ) larva migrans
  4. ঘ) E. Granulosus
ব্যাখ্যা
Dog is the definitive host in E. Granulosus
১,৩২১.
Most common cause of of renal cell carcinoma-
  1. ক) non papillary carcinoma
  2. খ) papillary carcinoma
  3. গ) chromophobe type carcinoma
  4. ঘ) Urothelial carcinoma
ব্যাখ্যা
Non papillary carcinoma is most common cause of RCC
১,৩২২.
The female urethra develops mainly from the-
  1. Paramesonephric duct
  2. Mesonephric duct
  3. Vesicourethral canal
  4. Definitive urogenital sinus
১,৩২৩.
Fragility fracture occurs due to-
  1. Osteomalacia
  2. Osteopenia
  3. Malignancy
  4. Paget’s disease
১,৩২৪.
Neuroglial cell take part in formation of blood-brain-barrier
  1. ক) Oligodendrocyte
  2. খ) Astrocyte
  3. গ) Ependymal cell
  4. ঘ) Satellite cells (of ganglia)
ব্যাখ্যা
Astrocyte mainly takes part in formation of blood-brain-barrier
১,৩২৫.
Which is the main function of nucleolus?
  1. rRNA synthesis
  2. tRNA synthesis
  3. mRNA synthesis
  4. Synthesis of mitochondria
ব্যাখ্যা
Nucleolus:
Nucleolus is a highly basophilic spherical mass of heterochromatin in cells actively engaged in protein synthesis. The intense basophilia of nucleoli is due not to heterochromatin but to the presence of densely concentrated ribosomal RNA (rRNA).

Function of nucleolus: Ribosomal RNA (rRNA) synthesis
১,৩২৬.
Inhibitor of enzyme enolase
  1. Cyanide
  2. Na - k ATP ase
  3. Fluride
  4. Nerve gas
১,৩২৭.
Goitre likely to shrink with levothyroxine therapy
  1. Riedel’s thyroiditis
  2. Graves’ disease
  3. Hashimoto’s thyroiditis
  4. Transient thyroiditis
১,৩২৮.
Local factor influence wound healing -
  1. Glucocorticoids
  2. Types of tissues
  3. Diabetes malitus
  4. Nutrition
ব্যাখ্যা
Explanation :
Local factor influence wound healing -
Local blood supply
Denervation
Local infection
Foreign body
Haematoma
Necrotic tissue
Mechanical stress
Protection ( dressing)
Surgical techniques
Types of tissues
১,৩২৯.
'A person who pretends to be ill in order to avoid having to work' is called -
  1. Zealot
  2. Malingerer
  3. Guileless
  4. Gullible
ব্যাখ্যা
• Malingerer (Noun)
English Meaning: A person who pretends to be ill in order to avoid having to work.
Bangla Meaning: যে ব্যক্তি কর্তব্য এড়াতে অসুস্থতার ভান করে।

• অন্য অপশনগুলোর মধ্যে - 
• Zealot (Noun)
English Meaning: A person who has very strong opinions about something, and tries to make other people have them too.
Bangla Meaning: কোনো বিশেষ আদর্শ দল, গোষ্ঠী বা ধর্মমত বিষয়ে প্রবল ও আপসহীন আগ্রহ-উদ্দীপনা প্রকাশ করে এমন ব্যক্তি; অন্ধ সমর্থক; গোঁড়া মৌলবাদী।

• Guileless (adjective)
English Meaning: Honest and direct.
Bangla Meaning: প্রতারণাহীন।

• Gullible (adjective)
English Meaning: Easily deceived or tricked, and too willing to believe everything that other people say.
Bangla Meaning: সহজে প্রতারণাযোগ্য।

Source: Live MCQ Lecture.
১,৩৩০.
Feature of innate immunity
  1. ক) Non specific
  2. খ) Slow
  3. গ) Has memory
  4. ঘ) Antibody dependent
১,৩৩১.
VIPoma is related to following electrolyte
  1. Na
  2. Ca
  3. Mg
  4. K
১,৩৩২.
Morphological pictures of peptic ulcer-
  1. ক) Superficial thin layer of granulation tissue
  2. খ) base of inflammatory tissue
  3. গ) Superficial layer of necrotic debris
  4. ঘ) Erosion of mucosal surface
ব্যাখ্যা
Superficial layer of necrotic debris is morphological pictures of peptic ulcer
১,৩৩৩.
Test to demonstrate anatomy of pancreas prior to surgery
  1. ক) ERCP
  2. খ) MRCP
  3. গ) USG
  4. ঘ) CT
ব্যাখ্যা
Reference: Davidson 23rd; P-841
১,৩৩৪.
Tract carries pain and temperature from opposite side
  1. ক) Spinothalamic tract
  2. খ) Dorsal column
  3. গ) Corticospinal tract
  4. ঘ) Geniculocalcarine tract
ব্যাখ্যা
Tract carries pain and temperature from opposite side is spinothalamic tract.
১,৩৩৫.
A 65-year-old woman with chronic knee pain, worse with activity, has X-rays showing joint space narrowing, osteophytes, and subchondral sclerosis. These radiographic findings are characteristic of:
  1. Gouty arthritis
  2. rheumatoid arthritis
  3. Osteoarthritis
  4. Psoriatic arthritis
ব্যাখ্যা
These are the classic radiographic hallmarks of osteoarthritis. Joint space narrowing indicates cartilage loss, osteophytes are bony outgrowths at joint margins, and subchondral sclerosis refers to increased bone density beneath the cartilage.
১,৩৩৬.
Most common site of pancreatic cancer
  1. ক) head
  2. খ) Body
  3. গ) Tail
  4. ঘ) entire gland
ব্যাখ্যা
No explanation added.
১,৩৩৭.
Layer of epidermis only present in thick skin
  1. ক) Corneum
  2. খ) Lucidum
  3. গ) Granulosum
  4. ঘ) Spiunosum
১,৩৩৮.
Austin Flint murmur is found in
  1. ক) MS
  2. খ) MR
  3. গ) TR
  4. ঘ) AR
ব্যাখ্যা
Reference: Davidson 23rd; P-524
১,৩৩৯.
Gastric ulcer most commonly occurs in which of the following site?
  1. ক) Body of stomach
  2. খ) Greater Curvature
  3. গ) Lesser curvature
  4. ঘ) Funus of Stomach
ব্যাখ্যা
Explanation: 90% of gastric ulcers are situated on the lesser curve within the antrum or at the junction between body and antral mucosa
১,৩৪০.
Pacinian corpuscles are absent in
  1. ক) Skeletal muscle
  2. খ) Tendons
  3. গ) Skin
  4. ঘ) Joint capsule
১,৩৪১.
Haemophilia A occurs due to deficiency of
  1. ক) Factor VII
  2. খ) Factor VIII
  3. গ) Factor IX
  4. ঘ) Factor X
ব্যাখ্যা
Explanation: Factor VIII deficiency resulting in haemophilia A affects 1/10 000 individuals. It is the most common congenital coagulation factor deficiency
১,৩৪২.
Intracellular fluid contains large amount of
  1. Glucose
  2. Na
  3. K
  4. Bicarbonate
১,৩৪৩.
Anemic Hypoxia
  1. CO poisoining
  2. CN poisoining
  3. Narcotics
  4. Hamorrage
ব্যাখ্যা
Anemic Hypoxia
CO poisoining
Stagnant/Ischemic hypoxia
CCF,He,Shock
Histotoxic hypoxia
Cyanide Posoining,Narcotics
১,৩৪৪.
Carcinoma of breast metastasizes
  1. ক) Lymphatic route
  2. খ) Hematogenous route
  3. গ) Direct seeding of surfaces
  4. ঘ) Indirect seeding of cavity
ব্যাখ্যা
Carcinoma of breast metastasizes lymphatic route
১,৩৪৫.
Principal artery of Rectum—
  1. ক) Sup. rectal artery
  2. খ) Middle rectal
  3. গ) Median sacral
  4. ঘ) Inf. rectal
ব্যাখ্যা
Superior rectal artery is the principal artery of rectum.
১,৩৪৬.
Radiographic hallmarks in RA excludes
  1. ক) Joint effusions
  2. খ) Juxta-articular osteopenia with erosions
  3. গ) Widening of the joint space
  4. ঘ) Loss of articular cartilage
ব্যাখ্যা

Radiographic hallmarks are
 Joint effusions
 Juxta-articular osteopenia with erosions
 Narrowing of the joint space
 Loss of articular cartilage

১,৩৪৭.
Diet does not reduce risk for colorectal carcinoma -
  1. Red meat
  2. Calcium
  3. Folic acid
  4. Omega 3 fatty acid
ব্যাখ্যা
Explanation -
Diatary factors reduce risk for colorectal carcinoma -
Folic acid
Fibers
Calcium
Omega 3 fatty acid
১,৩৪৮.
Focal cerebral infarcts are most commonly
  1. ক) Inflammatory
  2. খ) Neoplastic
  3. গ) Traumatic
  4. ঘ) Embolic
১,৩৪৯.
Causative agent of 'pain' in acute inflammation -
  1. C5a
  2. Bradykinin
  3. Histamin
  4. Leukotrines
ব্যাখ্যা
Explanation :
Causetive agents of pain in acute inflammation :
Prostaglandin 
Bradykinin
Increased K+
Decreased pH
Tissue reaction
5-HT/ serotonin
১,৩৫০.
Cerebral ventricles are lined by which cells?
  1. Astrocytes
  2. Microglial Cells
  3. Oligodendrocytes
  4. Ependymal cells
ব্যাখ্যা

Astrocytes form the structural framework for neurons and control their biochemical environment, their foot processes adjoining small blood vessels and forming the blood–brain barrier (Fig.28.1).


Oligodendrocytes are responsible for the formation and maintenance of the myelin sheath, which surrounds axons and is essential for maintaining the speed and consistency of action potential propagation along axons. Peripheral nerves have axons invested in myelin made by oligodendrocytes (Schwann cells).

Microglial cells derive from monocytes/macrophages and play a role in fighting infection and removing damaged cells.

Ependymal cells line the cerebral ventricles.

১,৩৫১.
Which are the major sites of resistance of circulation?
  1. ক) Arteries
  2. খ) Arterioles
  3. গ) Capillaries
  4. ঘ) Veins
ব্যাখ্যা
Explanation:
Arterioles are the major site of the resistance to blood flow. So, arterioles are the stop clocks of the circulation.
১,৩৫২.
Negri bodies are found in
  1. ক) Poliomyelitis
  2. খ) Rabies
  3. গ) Mumps
  4. ঘ) Rubella
১,৩৫৩.
Leukocyte migration through endothelium is called-
  1. ক) Phagocytosis
  2. খ) Chemotaxis
  3. গ) Diapedesis
  4. ঘ) Margination
ব্যাখ্যা
Leukocyte migration through endothelium is called diapedesis
১,৩৫৪.
Ball & socket type of synovial joint is present in
  1. ক) Elbow
  2. খ) Wrist
  3. গ) Hip
  4. ঘ) Knee
১,৩৫৫.
Pulmonary trunk is derived from
  1. ক) Truncus arteriosus
  2. খ) Bulbus cordis
  3. গ) Primitive ventricle
  4. ঘ) Sinus venosus
১,৩৫৬.
Pulse pressure does not depend on
  1. ক) Age
  2. খ) Sex
  3. গ) Stroke volume
  4. ঘ) Arterial elastic constant
ব্যাখ্যা

Explanation:
Pulse pressure
Is the difference between systolic and diastolic pressure. Normal pulse pressure is 30 - 60 mm Hg (average 50 mm Hg).
Pulse pressure depends on three factors:
• Age
• Stroke volume
• Arterial elastic constant

১,৩৫৭.
Cellular aging results from
  1. ক) RNA repair defect
  2. খ) Telomere shortening
  3. গ) Normal growth factor signalling
  4. ঘ) Telomere lengthening
ব্যাখ্যা
Cellular aging results from telomere shortening
১,৩৫৮.
Fibrocartilage is present in-
  1. Menisci of knee
  2. Elbow joint
  3. Epiphysis
  4. Apex of arytenoid cartilage
১,৩৫৯.
Which is bone resorbing cell -
  1. Osteoblast
  2. Osteocyte
  3. Osteoclasts
  4. Glycoaaminoglycans
ব্যাখ্যা
Explanation :
Bone cell -
Osteoblast : Bone forming cell
Osteocyte - Control calcium and phosphate level in bone
Osteoclast - Bone resorbing cell.
১,৩৬০.
Symptom of hypoglycaemia is..
  1. ক) Polyuria
  2. খ) predilection for sweet foods
  3. গ) Nocturia
  4. ঘ) Sweating
১,৩৬১.
A fall in plasma Na+ concentration -?
  1. ক) results from excessive production of ADH
  2. খ) Decreases intracellular fluid volume
  3. গ) Increases plasma osmolarity
  4. ঘ) Is likely to cause thirst
ব্যাখ্যা
Reference- Rodde physiology/6th/Q-48
১,৩৬২.
Strawberry tongue in
  1. ক) Enteric fever
  2. খ) Measles
  3. গ) Scarlet fever
  4. ঘ) Chicken pox
১,৩৬৩.
Successful eradication of H. Pylori can be confirmed by-
  1. Rapid urease test
  2. Microbiological culture
  3. Urea breath test
  4. Lactose H2 breath test
ব্যাখ্যা
Davidson 24th Ed. Page: 799
১,৩৬৪.
Fatty change of the liver occurs in all of the following except -
  1. ক) Starvation
  2. খ) Protein energy malnutrition
  3. গ) Hemochromatosis
  4. ঘ) Obesity
ব্যাখ্যা
Ref:Robbins/9th/p-62
১,৩৬৫.
Common cause of NS in children
  1. ক) Minimal change disease
  2. খ) Focal segmental glomerulosclerosis
  3. গ) Membranous glomerulopathy
  4. ঘ) IgA nephropathy
ব্যাখ্যা
ABM 474
১,৩৬৬.
Calcium channel blocker having anti-arrhythmic effect is
  1. Amlodipine
  2. Nifedipine
  3. Diltiazem
  4. All
১,৩৬৭.
STI that can transmit through transplacental route
  1. ক) Neisseria
  2. খ) Chlamydia
  3. গ) Treponema
  4. ঘ) HSV
১,৩৬৮.
Which paranasal sinus is the first to develop?
  1. Frontal sinus
  2. Ethmoidal sinus
  3. Maxillary sinus
  4. Sphenoidal sinus
১,৩৬৯.
Cardinal feature of leprosy excludes..
  1. ক) Skin lesions, typically anaesthetic at tuberculoid end of spectrum
  2. খ) Thickened peripheral nerves
  3. গ) hyperpigmented patch
  4. ঘ) Acid-fast bacilli on skin smears or biopsy
১,৩৭০.
Source of gut infection from human M. tuberculosis
  1. ক) Swallowed after coughing
  2. খ) Abdominal surgery
  3. গ) Anal coitus
  4. ঘ) Undercooked meat
ব্যাখ্যা
Reference: Davidson 23rd; P-812
১,৩৭১.
Survival rate of carcinoid tumor is
  1. 95%
  2. 85%
  3. 75%
  4. 65%
১,৩৭২.
E. Histolytica is responsible for which vector borne disease?
  1. ক) Giardiasis
  2. খ) Amoebiasis
  3. গ) Loiasis
  4. ঘ) Kalazar
ব্যাখ্যা
Amoebiasis is caused by E. histolytica
১,৩৭৩.
Drug used in relapse phase of ALL-
  1. Daunorubicin
  2. Fludarabine
  3. Vincristine
  4. Prednisolone
১,৩৭৪.
Characteristic feature of Paget’s disease is-
  1. Bone pain
  2. Pathological fracture
  3. Deafness
  4. Isolated elevation in ALP
১,৩৭৫.
Example of synovial joint-
  1. Symphysis pubis
  2. Sacroiliac joint
  3. Costovertebral joint
  4. Costochondral joint
ব্যাখ্যা
Davidson page- 994
১,৩৭৬.
Most common cause of nephrotic syndrome in children is-
  1. Focal segmental glomerulosclerosis
  2. Minimal change disease
  3. Membranous nephropathy
  4. IgA nephropathy
ব্যাখ্যা
Davidson P-571
১,৩৭৭.
A 28-year-old male develops oligoarthritis (affecting a few joints), conjunctivitis, and urethritis approximately 2 weeks after a bout of infectious diarrhea. Which of the following is the most likely diagnosis?
  1. Gout
  2. Septic Arthritis
  3. Reactive Arthritis
  4. Psoriatic Arthritis
ব্যাখ্যা
The classic triad of arthritis, urethritis, and conjunctivitis (can't see, can't pee, can't climb a tree), occurring after a gastrointestinal or genitourinary infection, is highly indicative of Reactive Arthritis (formerly Reiter's syndrome).
22:40
 
 
১,৩৭৮.
Which of the followings act as taste recptor cell in taste bud?
  1. ক) Sustentacular cell
  2. খ) Type II cell
  3. গ) Type III cell
  4. ঘ) Basal cell
ব্যাখ্যা

Explanation : Type of Cells in Taste Bud
1. Type I cells or sustentacular cells
2. Type II cells
3. Type III cells
4. Type IV cells or basal cells.
Type I cells and type IV cells are supporting cells. Type III cells are the taste receptor cells. Function of type II cell is unknown.

Ref : Sembulingam 6th edition (Page- 1024)
১,৩৭৯.
Capillaries only have
  1. ক) Endothelium
  2. খ) Intima
  3. গ) Media
  4. ঘ) Adventitia
ব্যাখ্যা
Capillaries have only an endothelium, with no subendothelial layer or other tunics.
১,৩৮০.
To maintain normal H+ balance, total daily excretion of H+ should equal the daily
  1. Fixed acid production plus fixed acid ingestion
  2. HCO3− excretion
  3. HCO3− filtered load
  4. Titratable acid excretion
ব্যাখ্যা
Total daily production of fixed H+ from catabolism of proteins and phospholipids (plus any additional fixed H+ that is ingested) must be matched by the sum of excretion of H+ as titratable acid plus NH4+ to maintain acid–base balance.
১,৩৮১.
Which is not a part of Penile erection initiation
  1. S2
  2. S3
  3. S4
  4. S1
ব্যাখ্যা
In penile erection initial penile vascular engorgement ias controlled by PNS part of ANS( S2,S3,S4 segments of spinal cord)

Erection and ejaculation
Erection and ejaculation are regulated by the autonomic innervation of the penis. The parasympathetic stimulation is excitatory for the penis, as it causes the erection. The parasympathetic stimuli relax the smooth musculature of the corpora cavernosa and produce vasodilation in the helicine arteries. The helicine arteries then fill the corpora cavernosa, compressing the venous outflow from the penis. This process is called the veno-occlusive mechanism and it results with penile erection.

On the other hand, the inhibitory sympathetic stimuli cause the ejaculation when the critical level of sexual excitement has been reached. The ejaculation process can be divided into two phases. In the first phase, the sympathetic stimuli cause the vasoconstriction of helicine arteries, contraction of the smooth muscle cells within the septa of corpus spongiosum and contraction seminal vesicles and prostate. This results in accumulation of seminal fluid into the proximal part of the urethra. During the second phase, the bulbospongiosus muscle contracts  and expels the seminal fluid through the urethra (ejaculation). When the ejaculation is finished the penis returns into the flaccid state. An individual normally produces 3-5 ml of semen per one ejaculation which contains about 300 million sperm cells.

Snell 8th - 402
১,৩৮২.
Most Common Pulmonary feat in RA?
  1. Fibrosis
  2. Respiratory failure
  3. Sarcoisoisis
  4. Lung cancer
১,৩৮৩.
What is the normal site of implantation?
  1. ক) Fundus of uterus
  2. খ) Anterior or posterior wall of the body of the uterus
  3. গ) Internalos of the uterus
  4. ঘ) Cornue of the uterus
ব্যাখ্যা
Reference: Langman’s 13th; P-47
১,৩৮৪.
Splinter hemorrhage in nail indicates
  1. ক) NS
  2. খ) PEM
  3. গ) Psoriasis
  4. ঘ) Subacute bacterial endocarditis
ব্যাখ্যা

Nail:
 Pale – anemia
 Bluish – cyanosis
 Brittle – koilonychia (Due to IDA)
 Leukonychia – CLD, NS, PEM
 Splinter hemorrhage – sub acute bacterial endocarditis
 Mees line – arsenic poisoning
 Onycholysis – psoriasis

১,৩৮৫.
Which one is a water-soluble vitamin?
  1. ক) A
  2. খ) B
  3. গ) D
  4. ঘ) E
ব্যাখ্যা
Explanation: Vitamins are organic substances with key roles in certain metabolic pathways, and are categorised into those that are fat-soluble (vitamins A, D, E and K) and those that are water-soluble (vitamins of the B complex group and vitamin C).
১,৩৮৬.
Which finding on ECG suggests ventricular tachycardia (VT)?
  1. P waves before every QRS
  2. wide QRS
  3. PR interval prolongation
  4. Delta waves
ব্যাখ্যা
VT shows broad QRS (>140 ms) and AV dissociation
১,৩৮৭.
A 70-year-old woman presents with back pain, fatigue, and recurrent infections. Laboratory tests show hypercalcemia, anemia, and elevated serum protein levels. A peripheral blood smear reveals rouleaux formation. What is the most likely diagnosis?
  1. Multiple myeloma
  2. Chronic lymphocytic leukemia (CLL)
  3. Waldenström’s macroglobulinemia
  4. Hyperparathyroidism
ব্যাখ্যা
Stem Breakdown:

Back pain, fatigue, and recurrent infections: These symptoms suggest multiple myeloma, a plasma cell malignancy that causes bone pain, anemia, and immunodeficiency.
Hypercalcemia and anemia: Hypercalcemia is due to bone destruction (osteolytic lesions), and anemia results from bone marrow infiltration by malignant plasma cells.
Elevated serum protein levels and rouleaux formation: These findings suggest excess monoclonal proteins (M-protein) in the blood, which is characteristic of multiple myeloma.
Option Analysis:

A) Multiple myeloma: This is the correct diagnosis. Davidson and Harrison describe multiple myeloma as a malignancy of plasma cells, leading to bone destruction, anemia, hypercalcemia, renal dysfunction, and immunodeficiency. Rouleaux formation on a blood smear is due to high levels of circulating monoclonal proteins, which interfere with red blood cell separation.
B) Chronic lymphocytic leukemia (CLL): CLL is a malignancy of B lymphocytes and causes lymphadenopathy, fatigue, and increased susceptibility to infections. However, it does not cause hypercalcemia or rouleaux formation.
C) Waldenström’s macroglobulinemia: This condition is associated with the production of IgM monoclonal protein, which can cause hyperviscosity symptoms but does not typically cause bone pain, hypercalcemia, or rouleaux formation.
D) Hyperparathyroidism: Hyperparathyroidism causes hypercalcemia due to overproduction of parathyroid hormone, but it does not cause anemia, rouleaux formation, or elevated serum protein levels.
১,৩৮৮.
Carpal tunnel syndrome develops due to compression of which nerve?
  1. ক) Ulnar
  2. খ) Median
  3. গ) Radial
  4. ঘ) Common peroneal
ব্যাখ্যা
Reference: Davidson 23rd, Box-25.87
১,৩৮৯.
All are derived from the surface ectoderm, except-
  1. Anterior pituitary
  2. Enamel of teeth
  3. Dermis of skin
  4. Olfactory epithelium
ব্যাখ্যা
***Dermis in the head, face & neck is derived from the neural crest cells (neuroectoderm)
***Dermis is remaining parts of the body is derived from Paraxial mesoderm

১,৩৯০.
Cardiac cycle is the term used to describe the sequence of events that occur as the heart works to pump blood through the body. The opening of the atrioventricular(AV) valves occurs at about the same time in the cardiac cycle as-
  1. ক) Beginning of diastole
  2. খ) Beginning of systole
  3. গ) End of isovolumic contraction
  4. ঘ) First heart sound
ব্যাখ্যা
The second is a shorter, high-pitched “dub” (second sound), caused by vibrations associated with closure of the aortic and pulmonary valves just after the end of ventricular systole and beginning of diastole.
১,৩৯১.
Which of the following is responsible for hepatocelluler jaundice?
  1. ক) Choledocholithiasis
  2. খ) Parasitic infection
  3. গ) Paracetamol
  4. ঘ) Traumatic biliary strictures
ব্যাখ্যা
Explanation: Option A,B,D causes obstructive jaundice
১,৩৯২.
Which of the following movements of the eyeball will be affected in abducent nerve injury?
  1. Abduction
  2. Adduction
  3. Elevation
  4. Extorsion
ব্যাখ্যা
Abducent nerve supplies the lateral rectus. 

১,৩৯৩.
Example of positive feedback mechanism except-
  1. ক) Generation of nerve signals
  2. খ) LH surge
  3. গ) Control of blood pressure
  4. ঘ) Insulin secretion in response to high blood glucose.
ব্যাখ্যা
[Guyton 13th 7]
১,৩৯৪.
A patient with lung cancer presents with ptosis, miosis, and anhidrosis. Which syndrome is this?
  1. Superior vena cava syndrome
  2. Lambert-Eaton syndrome
  3. Carcinoid syndrome
  4. Horner’s syndrome
ব্যাখ্যা
Horner’s syndrome results from disruption of the sympathetic pathway, commonly due to a Pancoast tumor (apical lung cancer). This tumor can invade the brachial plexus and cervical sympathetic chain, causing the classic triad: ptosis (drooping eyelid), miosis (constricted pupil), and anhidrosis (lack of sweating). Its presence points to locally advanced disease, often requiring chemoradiotherapy.
১,৩৯৫.
A police officer forces a medical officer to falsify a postmortem report. This act may be punishable under
  1. section 193 – Fabrication of false evidence in judicial proceeding
  2. Section 191 – Giving false evidence
  3. Section 120B – Criminal conspiracy
  4. All of the above
ব্যাখ্যা
False Evidence (Section 191):
This section addresses the act of giving false evidence, which occurs when someone, legally bound to state the truth, makes a false statement knowing it to be false or not believing it to be true. 
Conspiracy (Section 120B):
This section deals with criminal conspiracies, where two or more people agree to commit an illegal act. The punishment for conspiracy depends on the severity of the planned offense, with harsher penalties for conspiracies to commit serious crimes. 
Judicial Fabrication (Section 193):
This section punishes the intentional giving or fabricating of false evidence in a judicial proceeding. The punishment for this offense can extend to seven years of imprisonment, with a potential fine. This section also encompasses instances where individuals give or fabricate false evidence in other cases, imposing a maximum sentence of three years and a fine.
১,৩৯৬.
Most common cause of chronic or relapsing diarrhoea
  1. ক) IBD
  2. খ) IBS
  3. গ) Entamoeba infestations
  4. ঘ) Giardiasis
ব্যাখ্যা
Reference: Davidson 23rd; P-783
Explanation : The most common cause is irritable bowel syndrome which can present with increased frequency of defecation and loose , watery or pellety stools.
১,৩৯৭.
GH levels are commonly undetectable, so a choice from the range of ‘stimulation’ tests is required:. Which is not a GH stimulation test
  1. Insulin-induced hypoglycaemia
  2. Glucagon
  3. Arginine
  4. Clonidine (in adult)
১,৩৯৮.
Arteriole and precapillary sphincter are
  1. ক) Distribution vessels
  2. খ) Resistance vessels
  3. গ) Exchange vessels
  4. ঘ) Capacitance or reservoir vessels
ব্যাখ্যা
Arteriole and precapillary sphincter are Resistance vessels
১,৩৯৯.
Calculate HCO3 deficit in a 70 kg man,measured HCO3=20 mmol/l
  1. 140
  2. 150
  3. 110
  4. 160
ব্যাখ্যা
HCO3 deficit= ( Normal HCO3- Measured HCO3)* HCO3 space

HCO3 space=30-50 % of TBW
১,৪০০.
The cornerstone of acute management for the joint symptoms of Reactive Arthritis involves:
  1. Long-term antibiotics
  2. Uric acid-lowering therapy
  3. Non-steroidal anti-inflammatory drugs (NSAIDs)
  4. High-dose systemic corticosteroids for prolonged periods
ব্যাখ্যা
NSAIDs are the first-line treatment for acute joint pain and inflammation in reactive arthritis. While antibiotics are given for the initial infection, they generally do not affect the course of the arthritis itself. Systemic corticosteroids may be used for severe, refractory cases but are not first-line.